1. Volume 118, Issue 5, Pages 829-834 (May 2000)
Controlled 15-year trial on screening for colorectal cancer in families with hereditary nonpolyposis colorectal cancer 
Heikki J. Järvinen*, Markku Aarnio*, Harri Mustonen*, Katja Aktan–Collan‡, Lauri A. Aaltonen‡, Päivi Peltomäki§, Albert De La Chapelle§, Jukka–Pekka Mecklin∥ 
Gastroenterology 
Volume 118, Issue 5, Pages (May 2000)
DOI: /S (00)
Copyright © 2000 American Gastroenterological Association Terms and Conditions

2. Fig. 1
Cumulative proportion of subjects free of CRC. aP = between the screening and control groups including all subjects. bP = between mutation-positive subjects of the screening and control groups.
Gastroenterology  , DOI: ( /S (00) )
Copyright © 2000 American Gastroenterological Association Terms and Conditions

3. Fig. 2
Locations of all neoplastic tumors detected within 15 years: (A) mutation-positive subjects (n = 85); (B) mutation-negative subjects (n = 83). ●, CRC; ⊚, metachronous CRC; ○, adenoma.
Gastroenterology  , DOI: ( /S (00) )
Copyright © 2000 American Gastroenterological Association Terms and Conditions

4. Fig. 3
Cumulative overall survival. aP = between the screening and control groups including all subjects. bP = 0.05 between mutation-positive subjects of the screening and control groups.
Gastroenterology  , DOI: ( /S (00) )
Copyright © 2000 American Gastroenterological Association Terms and Conditions