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Arterioscler Thromb Vasc Biol

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Presentation on theme: "Arterioscler Thromb Vasc Biol"— Presentation transcript:

1 Arterioscler Thromb Vasc Biol
Ultrasound-Enhanced Thrombolytic Effect of Tissue Plasminogen Activator–Loaded Echogenic Liposomes in an In Vivo Rabbit Aorta Thrombus Model—Brief Report by Susan T. Laing, Melanie Moody, Beverly Smulevitz, Hyunggun Kim, Patrick Kee, Shaoling Huang, Christy K. Holland, and David D. McPherson Arterioscler Thromb Vasc Biol Volume 31(6): May 18, 2011 Copyright © American Heart Association, Inc. All rights reserved.

2 Highlighting of thrombus in the rabbit abdominal aorta by tPA-loaded ELIP compared with saline (control) and empty ELIP (mean±SE; n=4; *P<0.05 vs control and empty ELIP). Highlighting of thrombus in the rabbit abdominal aorta by tPA-loaded ELIP compared with saline (control) and empty ELIP (mean±SE; n=4; *P<0.05 vs control and empty ELIP). Susan T. Laing et al. Arterioscler Thromb Vasc Biol. 2011;31: Copyright © American Heart Association, Inc. All rights reserved.

3 Thrombolytic effect of tPA-loaded ELIP with and without ultrasound application in a rabbit aorta clot model (mean±SE; n=4; *P<0.001 vs tPA only and empty ELIP+ultrasound). Thrombolytic effect of tPA-loaded ELIP with and without ultrasound application in a rabbit aorta clot model (mean±SE; n=4; *P<0.001 vs tPA only and empty ELIP+ultrasound). Susan T. Laing et al. Arterioscler Thromb Vasc Biol. 2011;31: Copyright © American Heart Association, Inc. All rights reserved.


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