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Calcification burden of the femoropopliteal artery demonstrating progression from a healthy artery with no calcification (0) to advanced calcific deposits spread throughout tunica media. Calcification burden of the femoropopliteal artery demonstrating progression from a healthy artery with no calcification (0) to advanced calcific deposits spread throughout tunica media. Note that presence of medial calcification can be independent of intimal disease and can originate in the middle of the wall or closer to internal or external elastic laminae. Alexey Kamenskiy et al. Arterioscler Thromb Vasc Biol. 2018;38:e48-e57 Copyright © American Heart Association, Inc. All rights reserved.
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