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CALR mutations in patients with essential thrombocythemia diagnosed in childhood and adolescence by Fiorina Giona, Luciana Teofili, Sara Capodimonti, Marica.

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Presentation on theme: "CALR mutations in patients with essential thrombocythemia diagnosed in childhood and adolescence by Fiorina Giona, Luciana Teofili, Sara Capodimonti, Marica."— Presentation transcript:

1 CALR mutations in patients with essential thrombocythemia diagnosed in childhood and adolescence
by Fiorina Giona, Luciana Teofili, Sara Capodimonti, Marica Laurino, Maurizio Martini, Deborah Marzella, Giovanna Palumbo, Daniela Diverio, Robin Foà, and Luigi Maria Larocca Blood Volume 123(23): June 5, 2014 ©2014 by American Society of Hematology

2 Characteristics of patients grouped according to their genotype.
Characteristics of patients grouped according to their genotype. (A) Frequency of different mutations among 34 patients with ET, median age, and median follow-up of each group. (B) Hematologic and clinical findings at diagnosis in each group of patients. Data on clonality of hematopoiesis are relative to the time of molecular testing. Only significant results are shown. CALR, CALR mutated; JAK2, JAK2V617F mutated; WT, wild type for JAK2, CALR, and MPL. Fiorina Giona et al. Blood 2014;123: ©2014 by American Society of Hematology


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