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Nucleic acids 2006-2007.

Published byTeguh Darmadi Modified over 5 years ago

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Presentation on theme: "Nucleic acids 2006-2007."— Presentation transcript:

1 Nucleic acids

2 Nucleic Acids Information storage

3 Nucleic Acids Function: genetic material stores information
genes blueprint for building proteins DNA  RNA  proteins transfers information blueprint for new cells blueprint for next generation DNA proteins

4 A T C G Isn’t this a great illustration!?

5 Nucleic Acids Examples: Structure: RNA (ribonucleic acid)
single helix DNA (deoxyribonucleic acid) double helix Structure: monomers = nucleotides DNA RNA

6 Nucleotides 3 parts nitrogen base (C-N ring) pentose sugar (5C)
ribose in RNA deoxyribose in DNA phosphate (PO4) group Nitrogen base I’m the A,T,C,G or U part! Are nucleic acids charged molecules? DNA & RNA are negatively charged: Don’t cross membranes. Contain DNA within nucleus Need help transporting mRNA across nuclear envelope. Also use this property in gel electrophoresis.

7 Dangling bases? Why is this important?
Nucleic polymer Backbone sugar to PO4 bond phosphodiester bond new base added to sugar of previous base polymer grows in one direction N bases hang off the sugar-phosphate backbone Dangling bases? Why is this important?

8 Pairing of nucleotides
Nucleotides bond between DNA strands H bonds purine :: pyrimidine A :: T 2 H bonds G :: C 3 H bonds The 2 strands are complementary. One becomes the template of the other & each can be a template to recreate the whole molecule. Matching bases? Why is this important?

9 H bonds? Why is this important?
DNA molecule Double helix H bonds between bases join the 2 strands A :: T C :: G H bonds = biology’s weak bond • easy to unzip double helix for replication and then re-zip for storage • easy to unzip to “read” gene and then re-zip for storage H bonds? Why is this important?

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