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Introduction CKD-MBD. Introduction CKD-MBD Regulation of PTH Secretion.

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Presentation on theme: "Introduction CKD-MBD. Introduction CKD-MBD Regulation of PTH Secretion."— Presentation transcript:

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2 Introduction CKD-MBD

3 Regulation of PTH Secretion

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5 Factors Contributing to Pathogenesis of Secondary Hyperparathyroidism

6 Clinical Manifestations Associated With Elevated PTH in CKD-MBD

7 Vitamin D Metabolism

8 Determinants of Vitamin D Status

9 Clinical Practice Guidelines for CKD-MBD

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11 Lack of Consensus on Normal Ranges of Vitamin D

12 Vitamin D Toxicity

13 Treatment Goals for Secondary Hyperparathyroidism in Patients With CKD

14 Managing Serum Levels of Phosphate

15 Treatment Options VDRAs and Calcimimetics

16 K/DOQI Recommendations for Vitamin D Supplementation in CKD (Stages 3 and 4)

17 VDRAs vs Placebo in Nondialysis Patients With CKD Stages 3 to 5

18 Paricalcitol vs Calcitriol for Secondary Hyperparathyroidism in Stage 3 or 4 CKD

19 Novel Therapy Extended-Release Calcifediol

20 Oral Extended-Release Calcifediol in Treatment of SHPT in Stage 3 or 4 CKD

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