1. Volume 121, Issue 4, Pages 812-821 (April 2014)
A Randomized, Controlled Trial of Corneal Collagen Cross-Linking in Progressive Keratoconus 
Christine Wittig-Silva, MD, Elsie Chan, FRANZCO, Fakir M.A. Islam, PhD, Tony Wu, BSc, BOrth&OphSc, Mark Whiting, FRANZCO, Grant R. Snibson, FRANZCO 
Ophthalmology 
Volume 121, Issue 4, Pages (April 2014)
DOI: /j.ophtha
Copyright © 2014 American Academy of Ophthalmology Terms and Conditions

2. Figure 1
Flow chart demonstrating randomization, number of eyes examined at each follow-up visit, and reasons for patients withdrawing from the trial. CXL = corneal collagen cross-linking.
Ophthalmology  , DOI: ( /j.ophtha )
Copyright © 2014 American Academy of Ophthalmology Terms and Conditions

3. Figure 2
Bar graph showing the mean change in maximum simulated keratometry value (Kmax) between baseline and 3, 6, 12, 24, and 36 months after treatment for the control and treatment groups. In the control group, there was a significant increase in Kmax compared with continued flattening observed in the treatment group. The columns represent the mean change in Kmax from baseline (ΔKmax) in diopters (D) and the error bars represent the standard error. CXL = corneal collagen cross-linking.
Ophthalmology  , DOI: ( /j.ophtha )
Copyright © 2014 American Academy of Ophthalmology Terms and Conditions

4. Figure 3
Bar graph showing the mean change in uncorrected visual acuity (UCVA) between baseline and 3, 6, 12, 24, and 36 months after treatment for the control and treatment groups. In the control group, the deterioration from baseline was significant only after 36 months (P = 0.034). In the treatment group, the improvement was statistically significant at 12, 24, and 36 months. The columns represent the mean change in UCVA from baseline (ΔUCVA) and the error bars represent the standard error. CXL = corneal collagen cross-linking; logMAR = logarithm of the minimum angle of resolution.
Ophthalmology  , DOI: ( /j.ophtha )
Copyright © 2014 American Academy of Ophthalmology Terms and Conditions

5. Figure 4
Graph showing corneal thickness measurements compared with baseline at 3, 6, 12, 24, and 36 months after treatment. The lines represent the mean change in the thinnest point from baseline (Δ) in micrometers (μm). The diamonds and squares represent measurements using computerized videokeratography (CVK) in the control group and treatment groups, respectively; the triangles and crosses represent measurements using ultrasound pachymetry (USP) in the control and treatment groups, respectively. CXL = corneal collagen cross-linking.
Ophthalmology  , DOI: ( /j.ophtha )
Copyright © 2014 American Academy of Ophthalmology Terms and Conditions

6. Figure 5
Slit-lamp photographs of a patient with mild, diffuse, corneal edema and a small paracentral infiltrate obtained (A) 1 week after corneal collagen cross-linking (CXL) and (B) 12 months after CXL demonstrating residual corneal scarring.
Ophthalmology  , DOI: ( /j.ophtha )
Copyright © 2014 American Academy of Ophthalmology Terms and Conditions