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Dyslipidemia and Diabetic Macular Edema

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1 Dyslipidemia and Diabetic Macular Edema
Radha Das, MS, FRCS, Rebecca Kerr, BSc, Usha Chakravarthy, FRCOphth, PhD, Ruth E. Hogg, BSc, PhD  Ophthalmology  Volume 122, Issue 9, Pages (September 2015) DOI: /j.ophtha Copyright © 2015 American Academy of Ophthalmology Terms and Conditions

2 Figure 1 Process of study selection. DME = diabetic macular edema.
Ophthalmology  , DOI: ( /j.ophtha ) Copyright © 2015 American Academy of Ophthalmology Terms and Conditions

3 Figure 2 Association between cholesterol levels and the presence or absence of diabetic macular edema (DME). Pooled estimates of mean differences for cholesterol in diabetic patients with DME were compared with those in diabetic patients without DME. CI = confidence interval; df = degrees of freedom; dL = deciliters; SD = standard deviation. Ophthalmology  , DOI: ( /j.ophtha ) Copyright © 2015 American Academy of Ophthalmology Terms and Conditions

4 Figure 3 Association between low-density lipoprotein (LDL) cholesterol levels and presence or absence of DME. Pooled estimates of mean differences for LDL cholesterol in diabetic patients with DME were compared with diabetic patients without DME. CI = confidence interval; df = degrees of freedom; dL = deciliters; DME = diabetic macular edema; LDL C = low-density lipoprotein cholesterol; SD = standard deviation. Ophthalmology  , DOI: ( /j.ophtha ) Copyright © 2015 American Academy of Ophthalmology Terms and Conditions

5 Figure 4 Association between triglyceride (TG) levels and presence or absence of DME. Pooled estimates of mean differences for TGs in diabetic patients with DME were compared with those in diabetic patients without DME. CI = confidence interval; df = degrees of freedom; DME = diabetic macular edema; SD = standard deviation. Ophthalmology  , DOI: ( /j.ophtha ) Copyright © 2015 American Academy of Ophthalmology Terms and Conditions

6 Figure 5 Association between high-density lipoprotein (HDL) cholesterol levels and the presence or absence of DME. Pooled estimates of mean differences for HDL cholesterol in diabetic patients with DME were compared with those in diabetic patients without DME. CI = confidence interval; df = degrees of freedom; DME = diabetic macular edema; HDL C = high-density lipoprotein cholesterol; SD = standard deviation. Ophthalmology  , DOI: ( /j.ophtha ) Copyright © 2015 American Academy of Ophthalmology Terms and Conditions

7 Figure 6 Relative risk for progression of hard exudates in the lipid-lowering group compared with placebo group. ACCORD = Action to Control Cardiovascular Risk in Diabetes; CI = confidence interval; df = degrees of freedom; FIELD = Fenofibrate Intervention and Event Lowering in Diabetes; M-H = Mantel–Haenszel. Ophthalmology  , DOI: ( /j.ophtha ) Copyright © 2015 American Academy of Ophthalmology Terms and Conditions

8 Figure 7 Relative risk for severity of diabetic macular edema in the lipid-lowering group compared with placebo group. ACCORD = Action to Control Cardiovascular Risk in Diabetes; CI = confidence interval; df = degrees of freedom; M-H = Mantel–Haenszel. Ophthalmology  , DOI: ( /j.ophtha ) Copyright © 2015 American Academy of Ophthalmology Terms and Conditions


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