1. Microfluidics Roadmap for the Life Sciences
FlowMap
Microfluidics Roadmap for the Life Sciences
Thilo Brenner & Jens Ducrée - IMTEK
MANCEF COMS
Commercialization of Micro and Nano Systems
September 8-11, 2003
The Krasnapolsky Hotel Amsterdam (NL)
September 10, 2003
Jens Ducrée - IMTEK

2. Project Sponsored by EU Partners FP 5 – IST 15 months Funding: 170 k€
IMTEK (project leader)
Wicht Technologie Consulting
Cranfield Biotechnology Center
HSG-IMIT
Yole Développment
    
Jens Ducrée

3. Markets for Microfluidics Markets for Microfluidics
Life Sciences
Markets for Microfluidics
Printing
Industrial
Automation
Industrial
Dispensers
Chem .Process
Engineering
Power Systems

4. Biotech Life Sciences Markets Ecology Fields of Application Proteomics
Cellomics
Genomics
Drug
Delivery
Lead
Generation
Biotech
Therapeutics
enabling
Artificial
Tissue
Drug
Discovery
Lead
Optimization
Medicine
Life Sciences
Diagnostics
Patient
Monitoring
Markets
Compound
Libraries
Ecology
Fields of
Application
Forensics
Food
Air
Agriculture
Water

5. µFluidic Technologies
Flow Control
Sensing
Valving
Pumping
Techniques
Flow Sensing
Biosensitive
Transduction
Onchip
Detection
Pipetting &
Dispensing
Particle
Counting
Fabrication
Technologies
Well Plate
Technology
Particle
Manipulation
Liquid
Handling
Laden Fluids
Particle-
Concentration
Separation
Microarray
Substrates
Onchip
Separation
Arraying
Microarrays
Onchip
Microreacting
Onchip
Micromixing
Lab-on-a-Chip

6. Market Research Roadmap External Internal Market Studies Mailings
EU Programs
Personal
Interviews
Conferences
Expert
Workshops
Expertise of
Consortium
Jens Ducrée

7. Background of Participants
Jens Ducrée

8. Current Status of µFluidic Technologies
Jens Ducrée

9. Advantages of Microfluidic Technologies
Jens Ducrée

10. Technical Significance
Jens Ducrée

11. Demands on µFluidic Technologies
Jens Ducrée

12. Market Drivers
Jens Ducrée

13. Hurdles for Commercial Success
Jens Ducrée

14. Materials – Current Use
Jens Ducrée

15. Materials – Future Use
Jens Ducrée

16. µFluidic Technologies - Current
Jens Ducrée

17. µFluidic Technologies - Future
Jens Ducrée

18. Most Promising Markets for µFluidics
Jens Ducrée

19. Market Estimate 2002
Jens Ducrée

20. Expected Market Growth
Jens Ducrée

21. Market Estimate 2008 Conservative estimate D&MD estimate CAGR of 19%
50% growth
1600 M$ in 2006
Jens Ducrée

22. Dissemination www.microfluidics-roadmap.com Public report Distribution
100+ pages
Fall 2003
Distribution
CDROM
Brochure
Jens Ducrée

23. Contact Jens Ducrée IMTEK Lab for MEMS Applications
University of Freiburg, Germany
Phone: +49 / 761 /
Jens Ducrée

24. Technological Environment
Complemetary
technologies
Upstream
technologies
Materials
Components
Downstream:
product /
service
concepts
Technology under investigation
Market demand
and supply
Product
technology
Production
technology
Competing systems
(close substitution)
Downstream systems based
on alternative technologies
(wider substitution)
Other upstream
technologies
Jens Ducrée

25. external impact factors internal impact factors
technology
under investigation
internal impact factors
Economic development
science
standards & legistation
market demand
politics
demography
competition
infrastructure
social value system
Jens Ducrée

26. Performance Envelope market drivers (pull) dimensions performance
technology capabilities
and constraints (push)
performance
envelope
dimensions
Jens Ducrée

27. Markets for Microfluidics Markets for Microfluidics
Life Sciences
Markets for Microfluidics
Printing
Industrial
Automation
Industrial
Dispensers
Chem .Process
Engineering
Power Systems

28. Inkjet Printing Printhead Ink Substrate Continuous On-Demand Porous
(Paper, ...)
Non-Porous
(Plastic, Metal, ...)
Ink Base
Colorant
Piezo
Thermal

29. Printheads
Jens Ducrée

30. Inkjet Ink Technology
Jens Ducrée

31. Markets for Microfluidics Markets for Microfluidics
Life Sciences
Markets for Microfluidics
Printing
Industrial
Automation
Industrial
Dispensers
Chem .Process
Engineering
Power Systems

32. Industrial Automation
Pneumatics
Flow Control
Sensors

33. Markets for Microfluidics Markets for Microfluidics
Life Sciences
Markets for Microfluidics
Printing
Industrial
Automation
Industrial
Dispensers
Chem .Process
Engineering
Power Systems

34. Industrial Dispensers
Agro- / Food
Technical
Glue
Solder
Lubricants
Flavors
Scents
Pheromones

35. Markets for Microfluidics Markets for Microfluidics
Life Sciences
Markets for Microfluidics
Printing
Industrial
Automation
Industrial
Dispensers
Chem .Process
Engineering
Power Systems

36. Chem. Process Engineering Micromixers Microdispersers Heat Exchangers
Chemical
Microreactors
IMM

37. Markets for Microfluidics Markets for Microfluidics
Life Sciences
Markets for Microfluidics
Printing
Industrial
Automation
Industrial
Dispensers
Chem .Process
Engineering
Power Systems

38. Power Systems Fuel Cells Micro- Combustors Fuel Processors Fluidic
Microthrusters
Steam
Reformers
Partial
Oxidation

39. Markets Product Groups
Drug Discovery
Lead
Generation
Lead
Optimization
Compund
Libraries
Markets
Liquid Handling
Microarrays
Lab-on-a-Chip
Liquid Handling
Liquid Handling
Product Groups
Jens Ducrée

40. Markets Product Groups
Medicine
Diagnostics
Markets
Therapeutics
Patient
Monitoring
Drug Delivery
Artifical Tissue,
Glands, Organs
Forensics
In-Vivo
In-Vitro
Diffusional
Flow
Microarrays
Lab-on-a-Chip
Lab-on-a-Chip
Fabrication
Flow Control
???
Lab-on-a-Chip
Biochemical
Sensors
Microarrays
Particle-Laden
Fluids
Biochemical
Sensors
Product Groups
Jens Ducrée

41. Markets Product Groups
Ecology
Markets
Agriculture
Food
Air
Water
Biochemical
Sensors
Biochemical
Sensors
Lab-on-a-Chip
Biochemical
Sensors
Biochemical
Sensors
Lab-on-a-Chip
Lab-on-a-Chip
Microarrays
Lab-on-a-Chip
Lab-on-a-Chip
Particle-Laden
Fluids
Particle-Laden
Fluids
Product Groups
Jens Ducrée

42. Markets Product Groups
Biotech
Genomics
Proteomics
Cellomics
Markets
Microarrays
Microarrays
Lab-on-a-Chip
Lab-on-a-Chip
Lab-on-a-Chip
Particle-Laden
Fluids
Flow Control
Product Groups
Jens Ducrée

43. µFluidic Technologies
Product Groups
Flow Control
Biochemical
Sensors
Liquid
Handling
Microarrays
Lab-on-a-Chip
Particle-Laden
Fluids
Pumping
Techniques
Biosensitive
Transduction
Pipetting &
Dispensing
Arraying
Onchip
Micromixing
Particle
Concentrating
Valving
Well Plate
Technology
Microarray
Substrates
Onchip
Microreacting
Particle
Manipulation
Flow Sensing
Onchip
Separation
Particle
Counting
Onchip Detection: Physical, Chemical, Electrical, Optical, …
µFluidic Technologies
Jens Ducrée

44. basic sciences applied sciences MEMS engineering
Biochemistry
Chemistry
Physics
Biology
Medicine
Micro-
optics
Hydro-
dynamics
Micro-
actuators
Mechanics
MEMS
Micro-
electronics
engineering
Micro-
sensors
Computing /
Bioinformatics

45. Technology Roadmapping
Business /
Market /
Drivers
purpose
(know-why)
Products /
Services /
Capabilities
delivery
(know-what)
No Market
Technologies /
R&D Programs
Knowledge /
Resources
STOP
resources
(know-how)
time
Jens Ducrée

46. Markets by Source of Sample
Cell culture
Cell extracts
Synthesis
Biotech
Drug
Discovery
Medicine
Ecology
Compound library
Synthesis
Patient
Blood
Urine, …
Nature
Infrastructure
Jens Ducrée

47. Opportunity vs Risk
Jens Ducrée

48. Technology Roadmapping - Forecast
Markets
Products
Technologies
Jens Ducrée

49. Requested Improvements
Jens Ducrée

50. Goal Microfluidics Life Sciences Microfluidics Life Sciences
Technology drivers
Business opportunities
Microfluidics Life Sciences
Market drivers
Technological opportunities
Jens Ducrée

51. Fabrication Technologies
Materials
Structuring
Surface
Modification
Mass Fabrication
Fabrication
Technologies
Sealing
Prototyping
Interfacing
Integration