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Glycodelin is present in pinopodes of receptive-phase human endometrium and is associated with down-regulation of progesterone receptor B  Anneli Stavreus-Evers,

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Presentation on theme: "Glycodelin is present in pinopodes of receptive-phase human endometrium and is associated with down-regulation of progesterone receptor B  Anneli Stavreus-Evers,"— Presentation transcript:

1 Glycodelin is present in pinopodes of receptive-phase human endometrium and is associated with down-regulation of progesterone receptor B  Anneli Stavreus-Evers, Ph.D., Erik Mandelin, M.D., Ph.D., Riitta Koistinen, Ph.D., Lusine Aghajnova, M.D., Ph.D., Outi Hovatta, M.D., Ph.D., Markku Seppälä, M.D., Ph.D.  Fertility and Sterility  Volume 85, Issue 6, Pages (June 2006) DOI: /j.fertnstert Copyright © 2006 American Society for Reproductive Medicine Terms and Conditions

2 FIGURE 1 Immunohistochemical staining of glycodelin in the human endometrium. (a) Endometrium obtained at LH+6. (b) Endometrium obtained at LH+9; glycodelin in glandular epithelium (arrow). (c and d) Endometrium obtained at LH+10. (e) Double staining of glycodelin and PRB in endometrium obtained at LH+7. (f) Negative control. (g) Transmission electron microscopy of cell surface at LH+6. The gold particles are circled in red (inset). (h) Transmission electron microscopy of cell surface at LH+8. The gold particles are circled in red (inset). Stavreus-Evers. Glycodelin and pinopodes. Fertil Steril 2006. Fertility and Sterility  , DOI: ( /j.fertnstert ) Copyright © 2006 American Society for Reproductive Medicine Terms and Conditions

3 FIGURE 2 (a) Glycodelin staining, as seen in transmission electron microscopy, days LH+6, LH+7, and LH+8. (b) Comparison of glycodelin staining (transmission electron microscopy) in endometrial tissue with and without pinopodes. (c) Staining intensity of glycodelin (open circles) and PRB (solid circles) in human endometrium. (d) Immunohistochemical staining of glycodelin in relation to temporal appearance of pinopodes. Stavreus-Evers. Glycodelin and pinopodes. Fertil Steril 2006. Fertility and Sterility  , DOI: ( /j.fertnstert ) Copyright © 2006 American Society for Reproductive Medicine Terms and Conditions

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