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Optimization of Radioembolic Effect with Extended-shelf-life Yttrium-90 Microspheres: Results from a Pilot Study  Robert J. Lewandowski, MD, Ahsun Riaz,

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Presentation on theme: "Optimization of Radioembolic Effect with Extended-shelf-life Yttrium-90 Microspheres: Results from a Pilot Study  Robert J. Lewandowski, MD, Ahsun Riaz,"— Presentation transcript:

1 Optimization of Radioembolic Effect with Extended-shelf-life Yttrium-90 Microspheres: Results from a Pilot Study  Robert J. Lewandowski, MD, Ahsun Riaz, MD, Robert K. Ryu, MD, Mary F. Mulcahy, MD, Kent T. Sato, MD, Laura M. Kulik, MD, Vanessa L. Gates, MS, Talia Baker, MD, Reed Omary, MD, Riad Salem, MD  Journal of Vascular and Interventional Radiology  Volume 20, Issue 12, Pages (December 2009) DOI: /j.jvir Copyright © 2009 SIR Terms and Conditions

2 Figure 1 Waterfall display of change in target lesions following treatment plotted against frequency of occurrence. Journal of Vascular and Interventional Radiology  , DOI: ( /j.jvir ) Copyright © 2009 SIR Terms and Conditions

3 Figure 2 Pretreatment CT scan demonstrates a large, multiseptated, 18-cm-diameter metastasis in the right lobe of the liver (arrow) from a neuroendocrine primary. The patient was treated with 40 GBq (2 × 20 GBq vials, 16 million microspheres) decayed to 4.7 GBq, corresponding to 110 Gy. Journal of Vascular and Interventional Radiology  , DOI: ( /j.jvir ) Copyright © 2009 SIR Terms and Conditions

4 Figure 3 CT scan obtained after one treatment shows a substantial reduction in the size of the multiseptated lesion (arrows) and a decrease in the amount of enhancing tissue (representing necrosis); findings are indicative of a response to treatment. Journal of Vascular and Interventional Radiology  , DOI: ( /j.jvir ) Copyright © 2009 SIR Terms and Conditions

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