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Case Discussion/Conclusions

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Presentation on theme: "Case Discussion/Conclusions"— Presentation transcript:

1 Case Discussion/Conclusions
Severe Esophageal Stricture in a Child after Ingestion of a Callus Remover Product Jennifer Plumb, MD, MPH1, Stephen J Fenton, MD2, Richard Thomas, PharmD, DABAT3, Robert G Bolte, MD1, E Martin Caravati, MD, MPH4 1University of Utah, Division of Pediatric Emergency Medicine, 2University of Utah, Division of Pediatric Surgery, 3Primary Children’s Hospital, Intermountain Healthcare, 4University of Utah, Division of Emergency Medicine Case Discussion/Conclusions Case Report Potassium hydroxide (KOH) ingestion can cause esophageal injury and potential stricture formation. This case describes a delayed presentation of a severe esophageal stricture after ingestion of a widely available beauty product.  This child swallowed an unknown quantity of callus remover containing KOH, not in a child-resistant container. His initial well appearance was deceptive and endoscopy was not performed. Unfortunately, he later presented with severe delayed effects of his exposure. He subsequently developed an extensive stricture of nearly the entire length of the esophagus. Despite several interventions, he remains dependent on gastrostomy tube feedings, and will continue to require serial dilatations and possibly esophageal replacement. Commercial callus and wart remover products should be required to have child-resistant closures and list the percentage of KOH and other caustics on their product label An 11 month-old boy presented to an ED after possible ingestion of a callus remover product (Gena® Callus Off™). He was playing with a small bottle without child-resistant lid. Parents estimated the bottle was in his mouth for 5-10 sec, unknown amount of liquid possibly ingested. Initial ED Evaluation: Within 1 hour of ingestion No reported symptoms since exposure Normal exam, slight white plaque reported at base of the tongue Product ingredients listed in order are: water, potassium hydroxide, glycerin, propylene glycol, and acrylates. No ingredient quantities or concentrations on the label or website PC was consulted He tolerated an oral challenge and was observed for 1 hour prior to discharge Return ED Evaluation: 18 days later Presented to our ED with several days of gagging and vomiting, 24 hours intolerance to liquids No history of respiratory symptoms, fever, or weight loss Physical exam and vital signs normal, BMP and CBC normal Esophagram revealed a severe esophageal stricture extending from the carina to the gastroesophageal junction Admitted and had gastrostomy tube placement for enteral access Continued Effects: 10 months from exposure Undergoing esophageal dilatations every 2 weeks Course complicated by a gastric and esophageal perforation requiring abdominal exploration, gastric repair, and endoscopic covered esophageal stent placement  Initially only safely able to dilate to 8mm, most recently to 13.5 mm Still has dysphagia with some solids but clinically improved          18 days after exposure – Esophagram findings of severe stricture 19 days after exposure - Endoscopy images showing mucosal injury and stricture Dilatation and stent placement images Endoscopy Images courtesy of Dr. Stephen Fenton


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