1. Photo by gunnisal, Flickr Instituto Nacional de Saúde de Moçambique Novemer 3, 2009 An HDR CUH2A Initiative

2. Instituto Nacional de Saúde de Moçambique Design Review – 22 September 2009 An HDR CUH2A Initiative Introduction

3. Instituto Nacional de Saúde de Moçambique Design Review – 22 September 2009 An HDR CUH2A Initiative CUH2A CDC NIH Stanford Pfizer Cleveland Clinic

4. Instituto Nacional de Saúde de Moçambique Design Review – 22 September 2009 An HDR CUH2A Initiative Infectious Diseases Institute (Uganda) Regional Clinical Diagnostic Labs (Tanzania)

5. Instituto Nacional de Saúde de Moçambique Design Review – 22 September 2009 An HDR CUH2A Initiative Partnerships Programming Concept Design Peer Review Architecture Construction global local public-private

6. Instituto Nacional de Saúde de Moçambique Design Review – 22 September 2009 An HDR CUH2A Initiative Facility Goals

7. Instituto Nacional de Saúde de Moçambique Design Review – 22 September 2009 An HDR CUH2A Initiative Facility Goal = Strategic Goal Strengthen Essential NPHI Functions: Laboratory Science/Research Surveillance Training Outbreak investigation and control Meet International Standards

8. Instituto Nacional de Saúde de Moçambique Design Review – 22 September 2009 An HDR CUH2A Initiative Current Facility Conditions Insufficient Capacity Lack of Critical Functional Spaces Unsafe Conditions Inadequate Quality Management Unproductive Work Environment

9. Instituto Nacional de Saúde de Moçambique Design Review – 22 September 2009 An HDR CUH2A Initiative New Facility Features Enables NPHI strategic mission: Labs for laboratory science/research Offices for surveillance Team spaces for outbreak investigation and control Classrooms for training Co-locates all current NIH functions Provides work space for 160 NIH staff 8000 square meters on 3 floors

10. Instituto Nacional de Saúde de Moçambique Design Review – 22 September 2009 An HDR CUH2A Initiative Design

11. Instituto Nacional de Saúde de Moçambique Design Review – 22 September 2009 An HDR CUH2A Initiative Site EN-1 Maputo EN-2 EN-4 NIH site ~20 km

12. Instituto Nacional de Saúde de Moçambique Design Review – 22 September 2009 An HDR CUH2A Initiative Building Concept

13. 1 st Floor Directors Sruite Human Resources / Finance / Data Processing Epidemiology Staff Reference Libray Multipurpose Room Accessioning Lab Shipping / Receiving Insectary Animal Care ~2,360 m 2 / ~25,400 SF + ~180 m2 / ~1,960 SF covered outdoor space Circulation 87 m 2 Building Support 427 m 2 Open Office 287 m 2 Amenity 291 m 2 Vertical Circulation 115 m 2 Covered Outdoor 180 m 2 Space Mechanical / Core 176 m 2 Vivarium 583 m 2 Insectary 128 m 2 BSL2 Lab 193 m 2 Lab Support 73 m 2

14. 1 st Floor Entry

15. 1 st Floor Grant Mgmt/Planning

16. 1 st Floor Public Health Training

17. 1 st Floor Vivarium/Insectarium

18. 2 nd Floor Bacteriology & Parasitology Department: - Fungal & Mycobacterial Isolation - Bacteriology & Serology - Parasite & Host Biology - Intestinal & Urinary - Teaching Laboratory Glass Wash Media Prep ~2,570 m 2 / ~27,700 SF Circulation 48 m 2 Building Support 108 m 2 Open Office 864 m 2 Conference 70.5 m 2 Vertical Circulation 115 m 2 Mechanical / Core 155.2 m 2 BSL 3 Lab 35.2 m 2 BSL2 Lab 498 m 2 Lab Support 683.4 m 2

19. 2 nd Floor Outbreak Investigations

20. 2 nd Floor Teaching Lab

21. 2 nd Floor Microbiology Labs

22. 3 rd Floor Virology & Cell Biology Department: - BSL-3 Lab - Virus Isolation - Molecular Biology & Genomics/Proteomics - Cellular Immunology Morphology & Immunoassay Mechanical / Core 155.2 m 2 BSL 3 Lab 118 m 2 BSL2 Lab 476 m 2 Lab Support 617.3 m 2 Circulation 48 m 2 Building Support 108 m 2 Open Office 864 m 2 Conference 70.5 m 2 Vertical Circulation 115 m 2 ~2,570 m 2 / ~27,700 SF

23. 3 rd Floor Surveillance Team Spaces

24. 3 rd Floor Microbiology Labs

25. 3 rd Floor Reference Lab (BSL-3)

26. Instituto Nacional de Saúde de Moçambique Design Review – 22 September 2009 An HDR CUH2A Initiative Engineering Systems Ventilation Fully Air Conditioned 100% outside air Pressurized air flow control Redundant systems Plumbing Separated lab supply and discharge systems Emergency eyewashes and showers Electrical Redundant systems Emergency Generator Uninterruptible Power for IT

27. 3 rd Floor Closing

28. Instituto Nacional de Saúde de Moçambique Design Review – 22 September 2009 An HDR CUH2A Initiative Instituto Nacional de Saúde de Moçambique

29. Design Review – 22 September 2009 An HDR CUH2A Initiative Closing Points Capacity for NIH mission Safe, secure, reliable Great place to work Catalyst for funding Pride of community

30. Instituto Nacional de Saúde de Moçambique Design Review – 22 September 2009 An HDR CUH2A Initiative Instituto Nacional de Saúde de Moçambique