1. Outcome of Periapical Lesions in a Rat Model of Type 2 Diabetes: Refractoriness to Systemic Antioxidant Therapy 
Carlos Frederico B. Wolle, MSc, Luciana A. Zollmann, BS, Patrícia O. Bairros, BS, Adriana Etges, PhD, Carlos E. Leite, MSc, Fernanda B. Morrone, PhD, Maria M. Campos, PhD 
Journal of Endodontics 
Volume 39, Issue 5, Pages (May 2013)
DOI: /j.joen
Copyright © 2013 American Association of Endodontists Terms and Conditions

2. Figure 1
Percentage of body weight gain (A), plasma insulin levels (B), catalase (C), and GSH (D) liver levels in animals submitted to chronic intake of 20% glucose solution. Effects of oral treatment with tempol (50 and 100 mg/kg). Columns represent the mean of 5 experiments, and vertical lines indicate the standard error of mean. *,#P < .05, **,##P < .01. p.o., by mouth.
Journal of Endodontics  , DOI: ( /j.joen )
Copyright © 2013 American Association of Endodontists Terms and Conditions

3. Figure 2
Extension of radiographic area of periapical lesions (A). Columns represent the mean of 5 animals (in duplicate), and vertical lines indicate the standard error of mean. Representative radiographic images of periapical lesions in control animals (B) or in glucose-fed rats (C). Effects of treatment with the antioxidant tempol at 50 mg/kg (D) and 100 mg/kg (E), respectively. Arrowheads, radiolucent areas indicating periapical lesions.
Journal of Endodontics  , DOI: ( /j.joen )
Copyright © 2013 American Association of Endodontists Terms and Conditions

4. Figure 3
Histologic scores of periapical lesions (A). Columns represent the mean of 5 animals (in duplicate), and vertical lines indicate the standard error of mean. Representative histologic images of periapical lesions in control animals (B) or in glucose-fed rats (C). Effects of treatment with the antioxidant tempol at 50 mg/kg (D) and 100 mg/kg (E), respectively. Arrowheads, extension of the inflammatory process.
Journal of Endodontics  , DOI: ( /j.joen )
Copyright © 2013 American Association of Endodontists Terms and Conditions