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Phenobarbital reduces EEG amplitude and propagation of neonatal seizures but does not alter performance of automated seizure detection  Sean R. Mathieson,

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Presentation on theme: "Phenobarbital reduces EEG amplitude and propagation of neonatal seizures but does not alter performance of automated seizure detection  Sean R. Mathieson,"— Presentation transcript:

1 Phenobarbital reduces EEG amplitude and propagation of neonatal seizures but does not alter performance of automated seizure detection  Sean R. Mathieson, Vicki Livingstone, Evonne Low, Ronit Pressler, Janet M. Rennie, Geraldine B. Boylan  Clinical Neurophysiology  Volume 127, Issue 10, Pages (October 2016) DOI: /j.clinph Copyright © 2016 International Federation of Clinical Neurophysiology Terms and Conditions

2 Fig. 1 (a) Comparison of median peak seizure amplitudes for pre- and post-Pb seizures in all neonates. Black line represents group median. (b) Change in median peak seizure amplitude for each baby after Pb. Clinical Neurophysiology  , DOI: ( /j.clinph ) Copyright © 2016 International Federation of Clinical Neurophysiology Terms and Conditions

3 Fig. 2 (a) Comparison of median number of EEG channels involved at peak of seizure pre- and post-Pb for all neonates. Black line represents group median. (b) Change in median number of EEG channels involved in seizure (peak) after Pb for each baby. Clinical Neurophysiology  , DOI: ( /j.clinph ) Copyright © 2016 International Federation of Clinical Neurophysiology Terms and Conditions

4 Fig. 3 Examples of pre- and post-Pb seizures for patient 5. (a) Pre-Pb seizure and (b) post-Pb seizure. Clinical Neurophysiology  , DOI: ( /j.clinph ) Copyright © 2016 International Federation of Clinical Neurophysiology Terms and Conditions

5 Fig. 4 Distribution of detection rates for all neonates pre- and post-phenobarbital. Black lines indicate median values. Clinical Neurophysiology  , DOI: ( /j.clinph ) Copyright © 2016 International Federation of Clinical Neurophysiology Terms and Conditions


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