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Cardiac comorbidity is an independent risk factor for radiation-induced lung toxicity in lung cancer patients  Georgi Nalbantov, Bas Kietselaer, Katrien.

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Presentation on theme: "Cardiac comorbidity is an independent risk factor for radiation-induced lung toxicity in lung cancer patients  Georgi Nalbantov, Bas Kietselaer, Katrien."— Presentation transcript:

1 Cardiac comorbidity is an independent risk factor for radiation-induced lung toxicity in lung cancer patients  Georgi Nalbantov, Bas Kietselaer, Katrien Vandecasteele, Cary Oberije, Maaike Berbee, Esther Troost, Anne-Marie Dingemans, Angela van Baardwijk, Kim Smits, André Dekker, Johan Bussink, Dirk De Ruysscher, Yolande Lievens, Philippe Lambin  Radiotherapy and Oncology  Volume 109, Issue 1, Pages (October 2013) DOI: /j.radonc Copyright © 2013 The Authors Terms and Conditions

2 Fig. 1 A nomogram for the multivariate model (with variable selection) for the prediction of maximal dyspnea ⩾2 within six months after RT (probability of max dyspnea ⩾2). Radiotherapy and Oncology  , DOI: ( /j.radonc ) Copyright © 2013 The Authors Terms and Conditions

3 Fig. 2 ROC curves for the multivariable model (with selected variables) for predicting maximal dyspnea ⩾2 within 6months after the start of RT on the training set (solid line, cross-validated AUC=0.72) and the validation set (dashed line, AUC=0.67), as well as the ROC curve for the model including only mean lung dose as a predictor (dotted line, AUC=0.50). Radiotherapy and Oncology  , DOI: ( /j.radonc ) Copyright © 2013 The Authors Terms and Conditions


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