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Predictive modelling for swallowing dysfunction after primary (chemo)radiation: Results of a prospective observational study  Miranda E.M.C. Christianen,

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Presentation on theme: "Predictive modelling for swallowing dysfunction after primary (chemo)radiation: Results of a prospective observational study  Miranda E.M.C. Christianen,"— Presentation transcript:

1 Predictive modelling for swallowing dysfunction after primary (chemo)radiation: Results of a prospective observational study  Miranda E.M.C. Christianen, Cornelis Schilstra, Ivo Beetz, Christina T. Muijs, Olga Chouvalova, Fred R. Burlage, Patricia Doornaert, Phil W. Koken, C. René Leemans, Rico N.P.M. Rinkel, Marieke J. de Bruijn, G.H. de Bock, Jan L.N. Roodenburg, Bernard F.A.M. van der Laan, Ben J. Slotman, Irma M. Verdonck-de Leeuw, Hendrik P. Bijl, Johannes A. Langendijk  Radiotherapy and Oncology  Volume 105, Issue 1, Pages (October 2012) DOI: /j.radonc Copyright © 2011 Elsevier Ireland Ltd Terms and Conditions

2 Fig. 1 Normal tissue complication probability curves for SWALM6 for each 10Gy increase in dose to the supraglottic larynx. Abbreviations: NTCP=normal tissue complication probability, PCM=pharyngeal constrictor muscle, MD SGL=mean dose supraglottic larynx. Radiotherapy and Oncology  , DOI: ( /j.radonc ) Copyright © 2011 Elsevier Ireland Ltd Terms and Conditions

3 Fig. 2 Normal tissue complication probability curves for patient rated swallowing dysfunction: (a). Liquids (b). Soft food (c). Solid food (d). Choking. Abbreviations: NTCP=normal tissue complication probability, PCM=pharyngeal constrictor muscle, NPC=nasopharyngeal cancer, OPC=oropharyngeal cancer, MD SGL=mean dose supraglottic larynx, EIM=oesophagus inlet muscle. Radiotherapy and Oncology  , DOI: ( /j.radonc ) Copyright © 2011 Elsevier Ireland Ltd Terms and Conditions

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