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Improvement of the functional capacity is associated with BDNF and autonomic modulation in Chagas disease  Márcia M.O. Lima, Maria Carmo P. Nunes, Bruno.

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Presentation on theme: "Improvement of the functional capacity is associated with BDNF and autonomic modulation in Chagas disease  Márcia M.O. Lima, Maria Carmo P. Nunes, Bruno."— Presentation transcript:

1 Improvement of the functional capacity is associated with BDNF and autonomic modulation in Chagas disease  Márcia M.O. Lima, Maria Carmo P. Nunes, Bruno Nascimento, Henrique S. Costa, Lidiane A.P. Sousa, Antonio Lúcio Teixeira, Manoel Otávio C. Rocha, Antonio Luiz P. Ribeiro  International Journal of Cardiology  Volume 167, Issue 5, Pages (September 2013) DOI: /j.ijcard Copyright © 2012 Elsevier Ireland Ltd Terms and Conditions

2 Fig. 1 Association between the variation of the 6MWD before and after the AET and ∆BDNF levels (A), baseline values of the BDNF (B), % of maximal age-predicted HR during symptom-limited exercise test (C), and HRV indexes rMSSD (D). Association between ∆BDNF levels before and after the AET and HRV indexes SDNN (E) and rMSSD (F). International Journal of Cardiology  , DOI: ( /j.ijcard ) Copyright © 2012 Elsevier Ireland Ltd Terms and Conditions

3 Fig. 2 Accuracy of the change in BDNF levels and basal SDNN values in predicting an improvement of at least 50m of 6MWD after AET, as evaluated by the ROC Curve. International Journal of Cardiology  , DOI: ( /j.ijcard ) Copyright © 2012 Elsevier Ireland Ltd Terms and Conditions


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