1. AIMS OF THE LECTURE
Identify the relapsing fever and the caused organism
Clarify the routs of transmission
Discuss the presentation and mention the differential diagnosis of this febrile illness.
Identify the systemic complications of the disease
Discuss the investigations needed to the diagnosis
Explain the important lines of treatment
Discuss the methods of prevention of the disease

2. Relapsing Fever

3. Defination
acute recurrent febrile illnesse caused by bacteria in the genus Rickettsia and Borrelia .
Tick-borne relapsing fever
• Louse-borne relapsing fever
a vector-borne disease transmitted by bites of lice or ticks

4. Onset is 5-15 days after bitten.
Symptoms
Onset is 5-15 days after bitten.
Sudden fever. For 10 days, than relapse
tachycardia.
Headache 95% , cough and chills in 90%.
Myalgias, Petechia bleeding
Hepato - splenomegaly.
CNS: coma, cranial neuropathy as Bell palsy, hemiplegia, meningitis, and fits

5. Poor prognostic signs include
High bilirubin and jaundice,
Unconsciousness
Bleeding tendency,
prolonged QT interval on ECG.

6. Diagnosis
Blood smear stained with Giemsa or Wright stain.

7. THERAPY Tetracycline or Doxycycline is very effective,
a Jarisch-Herxheimer reaction, fever,sweat tachycardia with hypotension..
Mortality rate is ** 1% with treatment
** 30-70% without treatment