1. Ohtahara syndrome is a very rare and devastating form of epileptic encephalopathy of very early infancy. Onset of seizures is mainly by 1 month of age and often within the first 10 days of life, sometimes prenatally or during the first 2–3 months after birth. Characteristic clinico-EEG features are tonic spasms and, less commonly, erratic focal motor seizures and hemiconvulsion with S-B pattern in the EEG occurring in both sleep and waking states. Although the etiologies of Ohtahara syndrome are heterogeneous, prenatal brain pathology such as a malformation of cortical development is suspected in most cases and metabolic disorders are rare. Evolution into West syndrome is often observed in surviving cases.4,6
Source: Epileptic Encephalopathy, Atlas of Pediatric EEG
Citation: Laoprasert P. Atlas of Pediatric EEG; 2011 Available at: Accessed: November 08, 2017
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