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Patients with IS caused by FCD frequently develop partial seizures that can precede, be simultaneous with, or follow the cluster of epileptic spasms. Spasms.

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Presentation on theme: "Patients with IS caused by FCD frequently develop partial seizures that can precede, be simultaneous with, or follow the cluster of epileptic spasms. Spasms."— Presentation transcript:

1 Patients with IS caused by FCD frequently develop partial seizures that can precede, be simultaneous with, or follow the cluster of epileptic spasms. Spasms can be easily controlled by ACTH or Vigabatrin. EEG epileptic foci tend to persist after spontaneous disappearance of the hypsarrhythmic pattern or after successful treatment. When spasms disappear, patients are left with focal epilepsy that is intractable to medical treatment, in contrast with IS. Antiepileptic drug (AED) treatment seems to be able to prevent the diffuse paroxysmal activity outside of the FCD that causes secondary generalization such as in IS, but the intrinsic epileptogenicity of the FCD is poorly aff ected by the AED.15,41 Source: Epileptic Encephalopathy, Atlas of Pediatric EEG Citation: Laoprasert P. Atlas of Pediatric EEG; 2011 Available at: Accessed: October 25, 2017 Copyright © 2017 McGraw-Hill Education. All rights reserved


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