1. Connective tissue disease are we managing properly
Dr Chandrashekara. S
ChanRe RICR
Bangalore

2. Connective tissue disease- concept and confusions
The name
The cause
The classification
The treatment

3. THE NAME The disease name implies different system
Target of concern are different
Causation is autoimmune
The disease included are changing
What all to be called CTD

4. Targets of concern in CTD
OF LESS CONCERN
The skin
The joints
The muscles when
very little
Systemic features
OF GREATER CONCERN
The kidney
The CNS
The PNS
The lung

5. Diseases under CTD ANA+ve SLE Scleroderma Dermatomyositis/Polymyositis
MCTD
UCTD
ANA-ve
Vasculitis

6. When to suspect-CTD Multi system disease
As a cause for damage to any of the enlisted target
unexplainable illness

7. CTD-a disease with spectrum
A disease with spectra in
severity
clinical manifestations
immunological profile
prognosis

8. Are we treating-CTD
Treating Disease
Treating symptoms

9. Treating a CTD-steps Understand the disease
place the disease according to spectra

10. Managing CTD Symptomatic therapy Helping to live better
Educating patient

11. CTD Disease modifying intervention
No ideal therapy exists
No drugs with few exceptional disease can produce life time remission

12. CTD Disease modifying Intervention
Large doses of steroid and other Immune-suppressive
Drugs like chloroquine and D-pencillamine-modify immune status.

13. KEY POINTS IN MANAGEMENT OF CTD
Life threatening or not
early identification prior to target organ damage and appropriate interventions to salvage organ
Symptomatic therapy with minimal adverse reactions.

14. KEY POINTS Therapy to CTD is individualized
Prognosis- In terms of survival has changed
In terms of everyday life (QOL)
has improved.

15. Conclusion CTD/CVD-Labeling is not an end. But it is beginning
Steps in management
Identify the variant
Asses the disease
Plan and execute therapy individually.