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A case report: Ulcerative colitis, treatment with an antibody against tumor necrosis factor (infliximab), and subsequent liver necrosis  Urpo Kinnunen,

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Presentation on theme: "A case report: Ulcerative colitis, treatment with an antibody against tumor necrosis factor (infliximab), and subsequent liver necrosis  Urpo Kinnunen,"— Presentation transcript:

1 A case report: Ulcerative colitis, treatment with an antibody against tumor necrosis factor (infliximab), and subsequent liver necrosis  Urpo Kinnunen, Martti Färkkilä, Heikki Mäkisalo  Journal of Crohn's and Colitis  Volume 6, Issue 6, Pages (July 2012) DOI: /j.crohns Copyright © 2012 European Crohn's and Colitis Organisation Terms and Conditions

2 Figure 1 Transaminases (AST and ALT), alkaline phosphatase (AFOS) and total bilirubin (BIL) at the time of the Remicade infusions given at 8week intervals. The 3rd infusion was not given because of elevated liver values. Hepatic transplantation was performed 10days later. The laboratory values are represented as times the normal upper limit. Journal of Crohn's and Colitis 2012 6, DOI: ( /j.crohns ) Copyright © 2012 European Crohn's and Colitis Organisation Terms and Conditions

3 Figure 2 Panacinar hepatic necrosis with ductular proliferation. H&E staining, original magnification 100×. Journal of Crohn's and Colitis 2012 6, DOI: ( /j.crohns ) Copyright © 2012 European Crohn's and Colitis Organisation Terms and Conditions

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