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Central dogma: from genome to proteins II: Translation

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Presentation on theme: "Central dogma: from genome to proteins II: Translation"— Presentation transcript:

1 Central dogma: from genome to proteins II: Translation
Haixu Tang School of Informatics

2 The genetic code

3 Reading frames

4 tRNA

5 Unusual nucleotides

6

7 Amino acid activation

8 Editing of tRNA activation

9 tRNA matching

10 Peptide synthesis

11 Head vs. tail polymerization

12 Ribosomes

13 Ribosome structures

14 Ribosome structure

15 A possible reaction mechanism

16 Translation initiation

17 Structure of a typical bacterial mRNA molecule

18 Translation termination

19 Simultaneous translation

20 The rescue of a bacterial ribosome

21 Frameshift

22 Creation of mature proteins

23 Co-translational folding

24 Protein folding

25 Molecular chaperones

26 Monitoring protein quality

27 Protein degragation

28 Ubiquitin

29 Protein aggregation

30 Protein cycle in eukaryotic cell

31


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