1. Learning Objectives
By the end of this lesson you should…
Be able to describe the principles of PET scanning
Be able to describe the structure of a PET scanner

2. Positron Emission Tomography
Learning Objectives
By the end of this lesson you should…
Be able to describe the principles of PET scanning
Be able to describe the structure of a PET scanner
PET?
Positron Emission Tomography

3. (The most widely used radiopharmaceutical is fluorodeoxyglucose)
Learning Objectives
By the end of this lesson you should…
Be able to describe the principles of PET scanning
Be able to describe the structure of a PET scanner
A radioisotope that undergoes β+ (or positron, e+) decay is combined with glucose and injected into the bloodstream.
(The most widely used radiopharmaceutical is fluorodeoxyglucose)
The glucose compound is absorbed into the body tissues and used as normal glucose in respiration

4. It is inhaled by the patient to enable lung function to be studied
Learning Objectives
By the end of this lesson you should…
Be able to describe the principles of PET scanning
Be able to describe the structure of a PET scanner
Alternatively, a positron emitting isotope of oxygen (O-15) can be used.
It is inhaled by the patient to enable lung function to be studied

5. Learning Objectives
By the end of this lesson you should…
Be able to describe the principles of PET scanning
Be able to describe the structure of a PET scanner
Detection
After a decay has occurred and a positron is released it will typically travel less than 1mm before annihilating with an electron.
This produces two gamma photons with energy of 511keV travelling in opposite directions

6. Be able to describe the principles of PET scanning
Learning Objectives
By the end of this lesson you should…
Be able to describe the principles of PET scanning
Be able to describe the structure of a PET scanner

7. Be able to describe the principles of PET scanning
Learning Objectives
By the end of this lesson you should…
Be able to describe the principles of PET scanning
Be able to describe the structure of a PET scanner
                                                                                                                          

8. The patient is surrounded by a ring of gamma ray detectors
Learning Objectives
By the end of this lesson you should…
Be able to describe the principles of PET scanning
Be able to describe the structure of a PET scanner
The patient is surrounded by a ring of gamma ray detectors
- scintillation detectors and photomultiplier tubes
A computer analyses the time differences in the detection of the two gamma rays
Processing the input to the array of detectors allows an image of the organ to be produced.
Colour is used to signify the amount of radiation being detected at a certain point.

9. Answer Q3 Page 208 Be able to describe the principles of PET scanning
Learning Objectives
By the end of this lesson you should…
Be able to describe the principles of PET scanning
Be able to describe the structure of a PET scanner
Answer Q3
Page 208

10. What does PET allow us to study?
Learning Objectives
By the end of this lesson you should…
Be able to describe the principles of PET scanning
Be able to describe the structure of a PET scanner
What does PET allow us to study?
We can compare the rates of respiration of the parts of organs

11. More gamma photons will be detected from regions of cancerous tissue
Learning Objectives
By the end of this lesson you should…
Be able to describe the principles of PET scanning
Be able to describe the structure of a PET scanner
Cancer
Cancer cells have a greater division and growth rate, requiring more energy
Clusters of cancer cells will take in more of the radiolabelled glucose
More gamma photons will be detected from regions of cancerous tissue

12. The heart shows up clearly and the kidneys can be seen
The heart shows up clearly and the kidneys can be seen. The brightest area shows that there is cancer in a rib.
heart
kidney
tumour

13. Allows the study of brain trauma, epilepsy, Alzheimers
Learning Objectives
By the end of this lesson you should…
Be able to describe the principles of PET scanning
Be able to describe the structure of a PET scanner
The Brain
Active parts of the brain will require more energy and hence will have a higher respiration rate
Allows the study of brain trauma, epilepsy, Alzheimers

14. Be able to describe the principles of PET scanning
Learning Objectives
By the end of this lesson you should…
Be able to describe the principles of PET scanning
Be able to describe the structure of a PET scanner

15. Be able to describe the principles of PET scanning
Learning Objectives
By the end of this lesson you should…
Be able to describe the principles of PET scanning
Be able to describe the structure of a PET scanner

16. Be able to describe the principles of PET scanning
Learning Objectives
By the end of this lesson you should…
Be able to describe the principles of PET scanning
Be able to describe the structure of a PET scanner

17. Combining PET and CT scanning in one machine
Learning Objectives
By the end of this lesson you should…
Be able to describe the principles of PET scanning
Be able to describe the structure of a PET scanner
Development of imaging techniques…
Combining PET and CT scanning in one machine
CT scan identifies bones and organs and superimposing the PET scan image over this allows easier location of tumour sites