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Myoung J. Kang, Alistair Ingram, Hao Ly, Kerri Thai, James W. Scholey 

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Presentation on theme: "Myoung J. Kang, Alistair Ingram, Hao Ly, Kerri Thai, James W. Scholey "— Presentation transcript:

1 Effects of diabetes and hypertension on glomerular transforming growth factor-β receptor expression 
Myoung J. Kang, Alistair Ingram, Hao Ly, Kerri Thai, James W. Scholey  Kidney International  Volume 58, Issue 4, Pages (October 2000) DOI: /j x Copyright © 2000 International Society of Nephrology Terms and Conditions

2 Figure 1 Western blot analysis and densitometry measures of transforming growth factor-βreceptor I (TGF-β RI) expression in spontaneously hypertensive rat (SHR) glomeruli after one week of hyperglycemia (A), after two weeks of hyperglycemia (B), and after insulin treatment to normalize blood glucose levels (C; N = 6, *P < 0.05). Kidney International  , DOI: ( /j x) Copyright © 2000 International Society of Nephrology Terms and Conditions

3 Figure 2 Western blot analysis and densitometry measures of TGF-β RII expression in SHR glomeruli after one week of hyperglycemia (A), after two weeks of hyperglycemia (B), and after one week of insulin treatment to normalize blood glucose levels (C; N = 6, *P < 0.05). Kidney International  , DOI: ( /j x) Copyright © 2000 International Society of Nephrology Terms and Conditions

4 Figure 3 Western blot analysis and densitometry measures of TGF-β RI expression (A) and TGF-β RII expression (B) in glomeruli from normal SHR (control) and uninephrectomized SHR (Unx, N = 6, *P < 0.05) after two weeks. Kidney International  , DOI: ( /j x) Copyright © 2000 International Society of Nephrology Terms and Conditions

5 Figure 4 Western blot analysis and densitometry measures of TGF-β RI expression (A) and TGF-β RII expression (B) in glomeruli from normal SHRs and normal WKY rats (N = 6). Kidney International  , DOI: ( /j x) Copyright © 2000 International Society of Nephrology Terms and Conditions

6 Figure 5 Western blot analysis and densitometry measures of TGF-β RI expression (A) and TGF-β RII expression (B) in glomeruli from control WKY rats and diabetic WKY rats (N = 6) after one week. Kidney International  , DOI: ( /j x) Copyright © 2000 International Society of Nephrology Terms and Conditions

7 Figure 6 Western blot analysis and densitometry measures of TGF-β RI expression (A) and TGF-β RII expression (B) in glomeruli from control WKY rats and uninephrectomized WKY rats (N = 6) after one week. Kidney International  , DOI: ( /j x) Copyright © 2000 International Society of Nephrology Terms and Conditions

8 Figure 7 Western blot analysis and densitometry measures of TGF-β RI expression (A) and TGF-β RII expression (B) in glomeruli from control WKY rats and uninephrectomized diabetic WKY rats (N = 4) after one week. Kidney International  , DOI: ( /j x) Copyright © 2000 International Society of Nephrology Terms and Conditions


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