Presentation is loading. Please wait.

Presentation is loading. Please wait.

World Health Organization

Published byCharlene George Modified over 5 years ago

Similar presentations

Presentation on theme: "World Health Organization"— Presentation transcript:

1 World Health Organization
10 September, 2018 Neglected Tropical Diseases: an Overview Department of Control of Neglected Tropical Diseases World Health Organization

2 Neglected Tropical Diseases
World Health Organization 10 September, 2018 Neglected Tropical Diseases Protozoan Infections Leishmaniasis (VL, CL and MCL) Human African trypanosomiasis (sleeping sickness) Chagas disease Helminth Infections Soil-transmitted helminth infections Ascariasis-Trichuriasis-Hookworm Lymphatic filariasis (elephantiasis) Onchocerciasis (river blindness) Schistosomiasis Dracunculiasis (guinea-worm disease) Cysticercosis and other zoonotic helminthiasis Viral Infections Dengue & dengue haemorrhagic fever Bacterial Infections Leprosy Trachoma Buruli ulcer

3 World Health Organization
10 September, 2018 NTDs in poor populations Previously neglected diseases Neglected tropical diseases TB HIV/AIDS Soil transmitted helminthiasis Schistosomiasis Lymphatic filariasis Onchocerciasis Leprosy Trachoma Leishmaniasis Buruli ulcer Chagas disease Human African trypanosomiasis Dengue & DHF … Anthrax Malaria Bovine tuberculosis Cysticercosis Echinococcosis Brucellosis Zoonotic trypanosomiasis Rabies Neglected zoonoses … or poor populations and (all) their (undermining) diseases ? Impact on poverty making interventions cost-effective

4 Global distribution of NTDs
World Health Organization Global distribution of NTDs 10 September, 2018 . Approximately 1 billion people are affected by more than one of NTDs

5 Countries affected by NTDs by income group
World Health Organization Countries affected by NTDs by income group 10 September, 2018 More than 70% of countries and territories affected by neglected tropical diseases are low-income and low middle-income countries 100% of low-income countries are affected by at least 5 neglected tropical diseases

6 World Health Organization
10 September, 2018 The Burden DALYs Deaths STDs excluding HIV STDs excluding HIV Diarrhoeal diseases Diarrhoeal diseases HIV/Aids HIV/Aids Childhood & vaccine preventable diseases Childhood & vaccine preventable diseases TB TB Other infectious and parasitic diseases Malaria Other infectious and parasitic diseases Malaria African trypanosomiasis, Chagas disease, schistosomiasis, leishmaniasis, lymphatic filariasis, onchocerciasis, leprosy, dengue, japanese encephalitis, trachoma, STH Source: World Health Report 2002

7 Annual deaths due to NTDs
World Health Organization 10 September, 2018 Annual deaths due to NTDs Revised estimates (The Lancet) Schistosomiasis ,000 – 200,000 Leishmaniasis ,000 Trypanosomiasis ,000 Hookworm ,000 Ascariasis/Trichuriasis ,000 Dengue (DHF) ,000 Chagas Disease ,000 Leprosy ,000 LF Onchocerciasis Trachoma Total > 500,000

8 World Health Organization
Health and poverty 10 September, 2018 Ill health is both a cause and a consequence of poverty: sick people are more likely to become poor and the poor are more vulnerable to disease and disability Good health is central to creating and sustaining the capabilities that poor people need to escape from poverty Good health is not just an outcome of development: it is a way of achieving development

9 Neglected tropical diseases (NTDs): a right-to-health issue
World Health Organization Neglected tropical diseases (NTDs): a right-to-health issue 10 September, 2018 NTDs almost exclusively affects poor and marginalized people in low-income countries, in rural areas and settings where poverty is widespread Discrimination is both cause and consequence of NTDs Health interventions and research and development have long been inadequate and under funded and the picture has changed only in recent years Some of the essential drugs against NTD are now available but other are still inadequate or unavailable

10 World Health Organization
10 September, 2018 Large scale interventions Lymphatic filariasis Leprosy Onchocerciasis Schistosomiasis Helminthiasis Trachoma Yaws Rapid Impact Interventions Improving access Case management and development of new tools Human African trypanosomiasis Chagas diseases Buruli ulcer Leishmaniasis Dengue Focused interventions Improving innovation

11 World Health Organization
10 September, 2018 Buruli ulcer, Chagas disease, human African trypanosomiasis, leishmaniasis… Common characteristics Affected populations are the poorest and most isolated Different epidemiological patterns – difficult to detect with a unified approach Diagnostic procedures and case management are expensive, difficult to implement in resource-limited field settings and require expertise The diseases cannot benefit from preventive treatment Innovative and Intensified Disease Management

12 World Health Organization
10 September, 2018 Paris – 11 septembre 2006 Control with current tools What do we need? Diagnostic procedures are not sensitive, cannot be used at field level and are expensive Treatment is costly, difficult to administer, can have serious side-effects and can become resistant Simple, efficient and inexpensive diagnostic tools Oral, inexpensive drugs that do not have side-effects Need for specialized services Integration within existing health structures is possible Integration is not possible Sustained control/elimination is difficult Sustained control/elimination is feasible

13 World Health Organization
10 September, 2018 Onchocerciasis, LF, schistosomiasis, STH… London – 04 May 2006 Management with existing tools No individual diagnosis required Safe, single dose, free or cheap drugs Integrated management by local health capacities X Specialized services

14 World Health Organization
10 September, 2018 Preventive chemotherapy Existing field-applicable tools Simple, cheap community diagnosis Large scale treatment of groups or communities in need Regular "preventive" treatment Coordinated use of a few drugs will have an impact on many diseases Sustained control / elimination

15 World Health Organization
10 September, 2018 MDA1 = MDA with IVM + ALB once/year T1 = ALB or MBD + PZQ, 6 months after, targeted to school age children LF+ ONCHO+ SCHISTO+ STH high MDA1 T1

16 World Health Organization
10 September, 2018 T1 = ALB or MBD + PZQ, once/year, targeted to school age children T3 = ALB or MBD, 6 months after, targeted to school age children LF- ONCHO- SCHISTO+ STH high T1 T3

17 WHO and its partners propose a new approach
World Health Organization WHO and its partners propose a new approach 10 September, 2018 Rapid impact interventions with long-lasting results Focus on populations to improve access to essential interventions Integrate "strategies" to improve effectiveness Education, environment, local empowerment core for success All-round care, no "bits and pieces" Preventive chemotherapy on large scale PHC reinforcement, capacitating and development Focused interventions and innovation Empowering peripheral system through training and equipment Advocate for access to care and mainstream society for the neglected Measure diseases and development indicators

18 Lymphatic filariasis (LF)
World Health Organization Lymphatic filariasis (LF) 10 September, 2018 Over 120 million people are currently infected and around 1.3 billion people in more than 80 countries are at risk of infection. Drugs used against lymphatic filariasis are either donated – albendazole and ivermectin, or very inexpensive DEC. Albendazole is donated to WHO by GlaxoSmithKline for mass administration to at-risk populations.

19 World Health Organization
10 September, 2018 Thank you for your attention

Download ppt "World Health Organization"

Similar presentations

R&D Financing by the Bill & Melinda Gates Foundation

R&D Financing by the Bill & Melinda Gates Foundation
FamiliesUSA The Neglected Tropical Diseases

FamiliesUSA The Neglected Tropical Diseases
Neglected Tropical Diseases and Malaria: The need for mapping.

Neglected Tropical Diseases and Malaria: The need for mapping.
Module 6 After the survey TAS Global Programme to Eliminate Lymphatic Filariasis (GPELF) Training in monitoring and epidemiological assessment of mass.

Module 6 After the survey TAS Global Programme to Eliminate Lymphatic Filariasis (GPELF) Training in monitoring and epidemiological assessment of mass.
The Work of WHO in the South-East Asia Region Member countries made steady progress in health development Health development WHO focused on country.

The Work of WHO in the South-East Asia Region Member countries made steady progress in health development Health development WHO focused on country.
10 FACTS ON NEGLECTED TROPICAL DISEASES Fact 1 More than 1 billion people are affected by one or more neglected tropical diseases (NTDs). They are named.

10 FACTS ON NEGLECTED TROPICAL DISEASES Fact 1 More than 1 billion people are affected by one or more neglected tropical diseases (NTDs). They are named.
Parasitic diseases: current and future challenges Data Source: Moran M, Guzman J, Abela Oversteegen L, Liyanage R, Omune B, Wu L, Chapman N, Gouglas D.

Parasitic diseases: current and future challenges Data Source: Moran M, Guzman J, Abela Oversteegen L, Liyanage R, Omune B, Wu L, Chapman N, Gouglas D.
Professor Alan Fenwick OBE SCI Imperial College London Schistosomiasis and STH control and elimination ICOSA (LF, Oncho and trachoma)

Professor Alan Fenwick OBE SCI Imperial College London Schistosomiasis and STH control and elimination ICOSA (LF, Oncho and trachoma)
The U.S. President’s Emergency Plan for AIDS Relief The Evolving HIV Prevention Strategy for IDUs in PEPFAR Amb. Eric Goosby US Global AIDS Coordinator.

The U.S. President’s Emergency Plan for AIDS Relief The Evolving HIV Prevention Strategy for IDUs in PEPFAR Amb. Eric Goosby US Global AIDS Coordinator.
1 ASPECTS OF COMPLICATIONS ARISING FROM NEGELCTED TROPICAL CO-INFECTIONS AND THEIR SOCIAL AND ECONOMIC IMPLICATIONS IN SUB SAHARAN AFRICA L.S. Luboobi,

1 ASPECTS OF COMPLICATIONS ARISING FROM NEGELCTED TROPICAL CO-INFECTIONS AND THEIR SOCIAL AND ECONOMIC IMPLICATIONS IN SUB SAHARAN AFRICA L.S. Luboobi,
This wormy world: consequences, co-infections and the challenge of field-based study designs Professor Celia Holland Department of Zoology School of Natural.

This wormy world: consequences, co-infections and the challenge of field-based study designs Professor Celia Holland Department of Zoology School of Natural.
Designing Strategies for Neglected Disease Research Lecture 1A Amy Kapczynski UC Berkeley Law From MSF Campaign for Access to Essential Medicines, AccessNews.

Designing Strategies for Neglected Disease Research Lecture 1A Amy Kapczynski UC Berkeley Law From MSF Campaign for Access to Essential Medicines, AccessNews.
CENTER FOR BIOLOGICAL SEQUENCE ANALYSIS Technical University of Denmark - DTU Department of systems biology Biopeople Tutorial 2011 Immunological Bioinformatics.

CENTER FOR BIOLOGICAL SEQUENCE ANALYSIS Technical University of Denmark - DTU Department of systems biology Biopeople Tutorial 2011 Immunological Bioinformatics.
Designing Strategies for Neglected Disease Research: What Innovations Do We Need? Julia Walsh MD MSc UCB School of Public Health

Designing Strategies for Neglected Disease Research: What Innovations Do We Need? Julia Walsh MD MSc UCB School of Public Health
V S Mazumdar Professor and Head Department of Preventive and Social Medicine Medical College Baroda.

V S Mazumdar Professor and Head Department of Preventive and Social Medicine Medical College Baroda.
Communicable Diseases

Communicable Diseases
Andrew Gray March 10, 2009 www.ubc-uaem.org. Poverty Basic nutrition and clean water Shelter Education Basic medical care (public health) Lack of access.

Andrew Gray March 10, Poverty Basic nutrition and clean water Shelter Education Basic medical care (public health) Lack of access.
LESSON 13.2: PARASITIC INFECTIONS Module 13: Global Health Obj. 13.2: Identify the types and characteristics of common parasitic infections.

LESSON 13.2: PARASITIC INFECTIONS Module 13: Global Health Obj. 13.2: Identify the types and characteristics of common parasitic infections.
NTDs and eye health: lessons learnt and opportunities for collaboration Adrian D Hopkins Director: Mectizan Donation Program Task Force for Global Health.

NTDs and eye health: lessons learnt and opportunities for collaboration Adrian D Hopkins Director: Mectizan Donation Program Task Force for Global Health.
Did you know...  That one in every six people on this globe suffers from a disease of poverty?  That ten million people die each year from diseases.

Did you know...  That one in every six people on this globe suffers from a disease of poverty?  That ten million people die each year from diseases.

Similar presentations

Ads by Google