1. CustomVue vs Conventional LASIK: one year study
David Chao-Kai Chang M.D. M.P.H.
Nobel Eye Clinic, Taipei, Taiwan
台灣諾貝爾眼科醫院
張朝凱醫師
Lady & Gentleman, good afternoon, now I’ll talk about CustomVue versus conventional LASIK, this is a one year study
2006年中國上海COOC會議

2. Introductions WFG-LASIK More predictable outcome Less induction of HOA
Better night vision
To compare outcomes of LASIK using conventional Visx S4 and CustomeVue wavefront system in Taiwan
We know wavefront guided LASIK is more predictable, less induce HOA and has better night vision, so I will present our experiences in Taiwan to compare the outcomes of conventional LASIK and CustomeVue wavefront guided LASIK
2006年中國上海COOC會議

3. Patients Recruitment period  July 1 2004 – June 30 2005
Conventional LASIK
(VISX S4)
1360 subjects  2685 eyes
CustomeVue LASIK
( Wavescan Version 3.5)
262 subjects  500 eyes
Patients were enrolled between July and June , so 2685 eyes having conventional LASIK and 500 eyes having CustomeVue LASIK were enrolled in this prospective study.
2006年中國上海COOC會議

4. Pre-OP Data Conventional CustomeVue (n= 2685) (n=500)
Age y/o y/o
M:F : :6.2
MRSE ± ±1.4
Cyl ± ±0.45
WRSE NE ±1.5
These are preoperative data including age, gender, spherical equivalent, cylinder and spherical aberrations. There is not significant difference between age, gender, SE and cylinder
2006年中國上海COOC會議

5. Results UCVA BCVA MRSE Wavefront HOA Contrast Sensitivity
F/U time: at 1day, 1 week, 1、3 、6 、12 month (Since July to June )
UCVA
BCVA
MRSE
Wavefront HOA
Contrast Sensitivity
Postoperatively, patients were followed at 1 day, 1week and at 1,3,6,12 months. Postoperative examinations included UCVA, BCVA, manifest refraction, contrast sensitivity and wavescan measurement. However, follow-up data at 12 months were available for 19% conventional eyes and 16% customeVue eyes
2006年中國上海COOC會議

6. Part1 UCVA-Conventional
This figure illustrates UCVA for conventional eyes at 1,3,6,12 months, at 12 months, 87% of eyes were equal or above 20/20.
87% of eyes achieved 20/20 UCVA at 12 Month Follow-Up
2006年中國上海COOC會議

7. 94% of eyes achieved 20/20 UCVA at 12 Month Follow-Up
Part1 UCVA-CustomeVue
This figure illustrates UCVA of CustomeVue eyes at 1,3,6,12 months, at 12 months, 94% of eyes were equal or above 20/20
94% of eyes achieved 20/20 UCVA at 12 Month Follow-Up
2006年中國上海COOC會議

8. Part2 Post-OP UCVA vs Pre-OP BSCVA - Conventional
This figure illustrates comparison between post-op UCVA ant pre-OP BCVA in conventional eyes
2006年中國上海COOC會議

9. Part2 Post-OP UCVA vs Pre-OP BSCVA - CustomeVue
This figure illustrates comparison between post-OP UCVA and Pre-OP BSCVA in CustomeVue eyes
2006年中國上海COOC會議

10. Part2 Loss BCVA Loss of ≧ 2 lines BCVA 1 mon 0.62% 0 3 mon 0.55% 0.3%
Conventional CustomeVue
Loss of ≧ 2 lines BCVA
1 mon %
3 mon % %
6 mon %
12 mon %
BCVA≦ 20/25
1 mon %
3 mon % %
6 mon %
12 mon %
In CustomeVue group, no eyes lost more than 2 lines of BCVA or BCVA were worse than 20/25 at 12 months.
2006年中國上海COOC會議

11. Part3 MRSE-Conventional
This figure shows the attempted versus achieved results of conventional eyes at months.
2006年中國上海COOC會議

12. Part3 MRSE-CustomeVue
This figure shows attempted versus achieved results of CustomeVue group at 1,3,6,12 months
2006年中國上海COOC會議

13. Part4 Change in HOA (µ) Conventional LASIK CustomeVue LASIK
The CustomeVue treatments had a significant lower mean increase in high order aberration than the conventional treatments.
Conventional LASIK
CustomeVue LASIK
2006年中國上海COOC會議

14. Part5 CS-Conventional
Contrast sensitivity were obtained by Vistech 6500 preoperatively and 6, 12 monts
2006年中國上海COOC會議

15. Part5 CS-CustomVue
Contrast sensitivity were more stable in CustomeVue eyes
2006年中國上海COOC會議

16. Discussion
We will discuss some issues
2006年中國上海COOC會議

17. Issue 1 – Stability Better vision obtained
UCVA ≧20/16 at 1、3、6、12 months F/U
CustomeVue LASIK ＞Conventional LASIK
Better vision stability
87% of conventional group achieved 20/20 UCVA at 12 months F/U
94% of CustomeVue group achieved 20/20 UCVA at 12 months F/U
Issue I, stability: in this study, CustomeVue eyes had better vision obtained and better vision stability
2006年中國上海COOC會議

18. Issue 2 - Safety In CustomeVue group at 3 month F/U
Loss of ≧ 2 lines BCVA: 0.3%
BCVA≦ 20/25 : 0.3%
Flap complications were the causes
CustomeVue LASIK is safe!
Some flap problem must be overcome!
Issue 2, safety: at 3 months, loss of BCVA in CustomeVue eyes only had 0.3 %, flap complication were the causes, so it’s safety!
2006年中國上海COOC會議

19. Issue 3 - Predicability MRSE ± 0.50D (12 months)
Conventional: CustomeVue = 76% :84%
MRSE ± 1.0 D (12 months)
Conventional: CustomeVue = 92% :95%
Not significant
Some undercorrection was found by CustomeVue
Nomogram building is important!
Issue 3, predicability The attempted versus achieved results at 12 months between conventional eyes and CustomeVue eyes were not significant, in the meantime, some undercorrection was noted for CustomeVue eyes.
2006年中國上海COOC會議

20. Issue 4 - Visual Quality
CustomeVue group had a significant improvement in post-op UCVA compared with pre-op BCVA
CustomeVue group had a significant lower mean increase in HOA than conventaional group
CustomeVue LASIK really has better visual quality
Higher patient satisfaction !
Issue 4, Visual quality, 73% of CustomeVue eyes had better post-op UCVA than their pre-op BCVA, and we also found customeVue eyes had lower mean increase in HOA, so Custome LASIK really has better vision quality and patients satisfication.
2006年中國上海COOC會議

21. Issue 5 - Scopotic Complains
Contrast sensitivity is more stable in CustomeVue group
Less HOA increase in CustomeVue group
CustomeVue LASIK less induce scopotic problems
However, pupil diameter is another important factor !
Issue 5, Scopotic Complains, CustomeVue eyes had more stable contrast sensitivity and less increase HOA , however, pupil diameter is more important factor!
2006年中國上海COOC會議

22. Thanks for your attentions!
2006年中國上海COOC會議