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Dimorphic variant of ductal carcinoma in situ of the breast

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Presentation on theme: "Dimorphic variant of ductal carcinoma in situ of the breast"— Presentation transcript:

1 Dimorphic variant of ductal carcinoma in situ of the breast
Nozomi Ueno, MD, Hajime Kuroda, MD, Yuji Kozuka, MD, Oi Harada, MD, Hiroyuki Kato, MD, Keiichi Kubota, MD, Yasuo Imai, MD  Human Pathology: Case Reports  Volume 10, Pages (November 2017) DOI: /j.ehpc Copyright © 2017 The Authors Terms and Conditions

2 Fig. 1 Ultrasound examination showed an irregular hypoechoic mass in the lower outer quadrant of the right breast. Human Pathology: Case Reports  , 92-95DOI: ( /j.ehpc ) Copyright © 2017 The Authors Terms and Conditions

3 Fig. 2 Craniocaudal (A) and mediolateral oblique (B) mammogram views of the right breast showing no obvious tumor lesion. Human Pathology: Case Reports  , 92-95DOI: ( /j.ehpc ) Copyright © 2017 The Authors Terms and Conditions

4 Fig. 3 Dimorphic DCIS on low-power view. The finding of typical DCIS architecture, such as a cribriform pattern, supports categorization as DCIS. Human Pathology: Case Reports  , 92-95DOI: ( /j.ehpc ) Copyright © 2017 The Authors Terms and Conditions

5 Fig. 4 Typical microscopic appearance of two-cell composition of dimorphic DCIS. A cluster of tumor cells with clear cytoplasm (dimorphic cells ⬅) are forming in front of tumor cells with eosinophilic cytoplasm (columnar cells ➩) on a high-power view. Human Pathology: Case Reports  , 92-95DOI: ( /j.ehpc ) Copyright © 2017 The Authors Terms and Conditions

6 Fig. 5 The immunohistochemistry for ER (A), p63 (B), E-cadherin (C) and AR (D). Human Pathology: Case Reports  , 92-95DOI: ( /j.ehpc ) Copyright © 2017 The Authors Terms and Conditions


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