Presentation is loading. Please wait.

Presentation is loading. Please wait.

Do adipose tissue-derived mesenchymal stem cells have the same osteogenic and chondrogenic potential as bone marrow-derived cells?  Gun-II Im, M.D., Yong-Woon.

Published byStephanie Cannon Modified over 6 years ago

Similar presentations

Presentation on theme: "Do adipose tissue-derived mesenchymal stem cells have the same osteogenic and chondrogenic potential as bone marrow-derived cells?  Gun-II Im, M.D., Yong-Woon."— Presentation transcript:

1 Do adipose tissue-derived mesenchymal stem cells have the same osteogenic and chondrogenic potential as bone marrow-derived cells?  Gun-II Im, M.D., Yong-Woon Shin, M.D., Kee-Byung Lee, M.D.  Osteoarthritis and Cartilage  Volume 13, Issue 10, Pages (October 2005) DOI: /j.joca Copyright © 2005 OsteoArthritis Research Society International Terms and Conditions

2 Fig. 1 Immunofluorescent staining for STRO-1 in BMMSCs (A); ATMSCs (B); peripheral blood monocyte (C), and CD34 in BMMSCs (D); ATMSCs (E); peripheral blood monocyte (F). Osteoarthritis and Cartilage  , DOI: ( /j.joca ) Copyright © 2005 OsteoArthritis Research Society International Terms and Conditions

3 Fig. 2 AP staining of BMMSCs after 2 weeks of culture in OM (A); control medium (B), and ATMSCs after 2 weeks of culture in OM (C); control medium (D). Osteoarthritis and Cartilage  , DOI: ( /j.joca ) Copyright © 2005 OsteoArthritis Research Society International Terms and Conditions

4 Fig. 3 Von Kossa staining of BMMSCs after 3 weeks of culture in OM medium (A); control medium (B), and ATMSCs after 3 weeks of culture in OM (C); control medium (D). Osteoarthritis and Cartilage  , DOI: ( /j.joca ) Copyright © 2005 OsteoArthritis Research Society International Terms and Conditions

5 Fig. 4 The appearance of BMMSCs (A) and ATMSCs (B) in the fibrin culture (5 days after seeding). Osteoarthritis and Cartilage  , DOI: ( /j.joca ) Copyright © 2005 OsteoArthritis Research Society International Terms and Conditions

6 Fig. 5 Chondrogenesis in the pellet culture. Hematoxylin eosin staining of BMMSCs cultured in CM (A); in control medium (B), ATMSCs cultured in CM (C); in control medium (D) after 4 weeks of culture. Safranin-O staining of BMMSCs in CM (E); in control medium (F), ATMSCs cultured in CM (G); in control medium (H). Immunohistochemical staining for type II collagen of BMMSCs in CM (J); in control medium (K), ATMSCs cultured in CM (L); in control medium (M). Normal human articular cartilage and subchondral bone were used as the control for Safranin-O staining (I) and type II collagen staining (N). Osteoarthritis and Cartilage  , DOI: ( /j.joca ) Copyright © 2005 OsteoArthritis Research Society International Terms and Conditions

7 Fig. 6 Chondrogenesis in the fibrin gel culture. Hematoxylin eosin staining of BMMSCs cultured in CM (A); in control medium (B), ATMSCs cultured in CM (C); in control medium (D) after 4 weeks of culture. Safranin-O staining of BMMSCs in CM (E); in control medium (F), ATMSCs cultured in CM (G); in control medium (H). Immunohistochemical staining for type II collagen of BMMSCs in CM (I); in control medium (J), ATMSCs cultured in CM (K); in control medium (L). Osteoarthritis and Cartilage  , DOI: ( /j.joca ) Copyright © 2005 OsteoArthritis Research Society International Terms and Conditions

Download ppt "Do adipose tissue-derived mesenchymal stem cells have the same osteogenic and chondrogenic potential as bone marrow-derived cells?  Gun-II Im, M.D., Yong-Woon."

Similar presentations

Treatment of a full-thickness articular cartilage defect in the femoral condyle of an athlete with autologous bone-marrow stromal cells  R. Kuroda, M.D.,

Treatment of a full-thickness articular cartilage defect in the femoral condyle of an athlete with autologous bone-marrow stromal cells  R. Kuroda, M.D.,
Variations in matrix composition and GAG fine structure among scaffolds for cartilage tissue engineering  J.K. Mouw, M.S., N.D. Case, Ph.D., R.E. Guldberg,

Variations in matrix composition and GAG fine structure among scaffolds for cartilage tissue engineering  J.K. Mouw, M.S., N.D. Case, Ph.D., R.E. Guldberg,
Expression pattern differences between osteoarthritic chondrocytes and mesenchymal stem cells during chondrogenic differentiation  P. Bernstein, C. Sticht,

Expression pattern differences between osteoarthritic chondrocytes and mesenchymal stem cells during chondrogenic differentiation  P. Bernstein, C. Sticht,
Hypoxia reduces the inhibitory effect of IL-1β on chondrogenic differentiation of FCS- free expanded MSC  T. Felka, R. Schäfer, B. Schewe, K. Benz, W.K.

Hypoxia reduces the inhibitory effect of IL-1β on chondrogenic differentiation of FCS- free expanded MSC  T. Felka, R. Schäfer, B. Schewe, K. Benz, W.K.
Basic science and clinical application of platelet-rich plasma for cartilage defects and osteoarthritis: a review  Y. Zhu, M. Yuan, H.Y. Meng, A.Y. Wang,

Basic science and clinical application of platelet-rich plasma for cartilage defects and osteoarthritis: a review  Y. Zhu, M. Yuan, H.Y. Meng, A.Y. Wang,
Chondrocytes extract from patients with osteoarthritis induces chondrogenesis in infrapatellar fat pad-derived stem cells  E. López-Ruiz, M. Perán, J.

Chondrocytes extract from patients with osteoarthritis induces chondrogenesis in infrapatellar fat pad-derived stem cells  E. López-Ruiz, M. Perán, J.
Single-stage cell-based cartilage repair in a rabbit model: cell tracking and in vivo chondrogenesis of human umbilical cord blood-derived mesenchymal.

Single-stage cell-based cartilage repair in a rabbit model: cell tracking and in vivo chondrogenesis of human umbilical cord blood-derived mesenchymal.
The beneficial effect of delayed compressive loading on tissue-engineered cartilage constructs cultured with TGF-β3  E.G. Lima, M.Phil., M.S., L. Bian,

The beneficial effect of delayed compressive loading on tissue-engineered cartilage constructs cultured with TGF-β3  E.G. Lima, M.Phil., M.S., L. Bian,
Synovial mesenchymal stem cells from osteo- or rheumatoid arthritis joints exhibit good potential for cartilage repair using a scaffold-free tissue engineering.

Synovial mesenchymal stem cells from osteo- or rheumatoid arthritis joints exhibit good potential for cartilage repair using a scaffold-free tissue engineering.
Hypoxia reduces the inhibitory effect of IL-1β on chondrogenic differentiation of FCS- free expanded MSC  T. Felka, R. Schäfer, B. Schewe, K. Benz, W.K.

Hypoxia reduces the inhibitory effect of IL-1β on chondrogenic differentiation of FCS- free expanded MSC  T. Felka, R. Schäfer, B. Schewe, K. Benz, W.K.
Mesenchymal stromal cells for cartilage repair in osteoarthritis

Mesenchymal stromal cells for cartilage repair in osteoarthritis
Z. Zhang, Y. Kang, Z. Zhang, H. Zhang, X. Duan, J. Liu, X. Li, W. Liao 

Z. Zhang, Y. Kang, Z. Zhang, H. Zhang, X. Duan, J. Liu, X. Li, W. Liao 
Immunomodulatory effect of mesenchymal stem cells following intra-articular injection in a model of osteoarthritis: a potential role for apoptosis  P.

Immunomodulatory effect of mesenchymal stem cells following intra-articular injection in a model of osteoarthritis: a potential role for apoptosis  P.
Subtractive gene expression profiling of articular cartilage and mesenchymal stem cells: serpins as cartilage-relevant differentiation markers  S. Boeuf,

Subtractive gene expression profiling of articular cartilage and mesenchymal stem cells: serpins as cartilage-relevant differentiation markers  S. Boeuf,
Chitosan–glycerol phosphate/blood implants increase cell recruitment, transient vascularization and subchondral bone remodeling in drilled cartilage defects 

Chitosan–glycerol phosphate/blood implants increase cell recruitment, transient vascularization and subchondral bone remodeling in drilled cartilage defects 
A review of the effects of insulin-like growth factor and platelet derived growth factor on in vivo cartilage healing and repair  M.B. Schmidt, Ph.D.,

A review of the effects of insulin-like growth factor and platelet derived growth factor on in vivo cartilage healing and repair  M.B. Schmidt, Ph.D.,
Repair of full-thickness femoral condyle cartilage defects using allogeneic synovial cell- engineered tissue constructs  M. Pei, F. He, B.M. Boyce, V.L.

Repair of full-thickness femoral condyle cartilage defects using allogeneic synovial cell- engineered tissue constructs  M. Pei, F. He, B.M. Boyce, V.L.
K.A. Payne, D.M. Didiano, C.R. Chu  Osteoarthritis and Cartilage 

K.A. Payne, D.M. Didiano, C.R. Chu  Osteoarthritis and Cartilage 
G.-I. Im, H.-J. Kim  Osteoarthritis and Cartilage 

G.-I. Im, H.-J. Kim  Osteoarthritis and Cartilage 
Aging-related inflammation in osteoarthritis

Aging-related inflammation in osteoarthritis

Similar presentations

Ads by Google