1. Multimodal Neural Monitoring
Group C
Kathy Dai, Brett Dixon, Wassim Khalil, Kylie McClanahan, Cody Phillips

2. people die of Heart Disease per year = 1 in 4 Deaths
610,000
people die of Heart Disease per year = 1 in 4 Deaths

3. Problem Coronary Artery Bypass Graft Surgery Neurological Injuries
Cardiopulmonary Bypass
Neurological Injuries
Loss of White Matter
Current practices to monitor the brain in cardiac surgery
Post-oximetry
Urinal catheter

4. Objective Brain “Cap” CSCE Cerebral Activity (EEG) Oxygen Content
Cerebral Blood Flow Velocity
System Blood Pressure
Temperature
CSCE
Easily-Readable Data
User-Friendly Interface

5. Background and Previous Work
Relevant technologies:
Cardiopulmonary Bypass (CPB)
Electroencephalogram (EEG)
Near-infrared spectroscopy (NIRS)
Previous research:
Neurocognitive dysfunction is prevalent
Monitoring the cerebral cortex can positively affect outcome
NIRS data
Oxygenation
Blood flow
Cerebral temperature

6. Design Requirements and Design Goals High Level Architecture
What the UI should display
UI will be used as alert
UI will be used for postoperative investigations
High Level Architecture
Real time regional monitoring of brain blood flow, oxygenation, temperature, electrophysiological activity
if oxygenation falls below a certain threshold. More advanced algorithms could possibly correlate multiple data points and make a comprehensive assessment of overall brain condition.
Data will be stored in the PC used to be retrieved again for investigation

8. Deliverables Design Document Data Information Software Releases
“Cap” design
Hardware and Software used
Data Information
How we analyzed the data to establish a normal
Software Releases
Multiple updates after initial deployment to get feedback from mentors and BMEGs
Test Cases
Well documented reports of continuous testing
Final Report
Wrap-up of project in its entirety