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Copyright © 2000 American Medical Association. All rights reserved.

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Presentation on theme: "Copyright © 2000 American Medical Association. All rights reserved."— Presentation transcript:

1 Copyright © 2000 American Medical Association. All rights reserved.
From: Gastrointestinal Tolerability of the Selective Cyclooxygenase-2 (COX-2) Inhibitor Rofecoxib Compared With Nonselective COX-1 and COX-2 Inhibitors in Osteoarthritis Arch Intern Med. 2000;160(19): doi: /archinte Figure Legend: Twelve-month cumulative incidence (by survival analysis) of discontinuation due to gastrointestinal adverse events. Relative risk for rofecoxib vs nonsteroidal anti-inflammatory drugs (NSAIDs) is 0.70 (95% confidence interval, ). Date of download: 10/14/2017 Copyright © 2000 American Medical Association. All rights reserved.

2 Copyright © 2000 American Medical Association. All rights reserved.
From: Gastrointestinal Tolerability of the Selective Cyclooxygenase-2 (COX-2) Inhibitor Rofecoxib Compared With Nonselective COX-1 and COX-2 Inhibitors in Osteoarthritis Arch Intern Med. 2000;160(19): doi: /archinte Figure Legend: Twelve-month cumulative incidence (by survival analysis) of dyspeptic-type gastrointestinal adverse events. Six- and 12-month relative risks for rofecoxib vs nonsteroidal anti-inflammatory drugs (NSAIDs) are 0.85 (95% confidence interval, ) and 0.88 (95% confidence interval, ), respectively. Dyspeptic-type gastrointestinal adverse events included acid reflux, dyspepsia, epigastric discomfort, heartburn, nausea, and vomiting. Date of download: 10/14/2017 Copyright © 2000 American Medical Association. All rights reserved.


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