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Invasive lobular breast cancer and its variants: How special are they for systemic therapy decisions?  Séverine Guiu, Anita Wolfer, William Jacot, Pierre.

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Presentation on theme: "Invasive lobular breast cancer and its variants: How special are they for systemic therapy decisions?  Séverine Guiu, Anita Wolfer, William Jacot, Pierre."— Presentation transcript:

1 Invasive lobular breast cancer and its variants: How special are they for systemic therapy decisions?  Séverine Guiu, Anita Wolfer, William Jacot, Pierre Fumoleau, Gilles Romieu, Franck Bonnetain, Maryse Fiche  Critical Reviews in Oncology / Hematology  Volume 92, Issue 3, Pages (December 2014) DOI: /j.critrevonc Copyright © 2014 Elsevier Ireland Ltd Terms and Conditions

2 Fig. 1 Morphological aspects of classic and pleomorphic invasive lobular carcinoma. (A) Invasive lobular carcinoma, classic type. (B)–(D) Invasive pleomorphic lobular carcinoma: pleomorphic atypical nuclei (A); loss of E-cadherin expression (C) (E-cadherin is expressed in normal ductal cells); and Ki-67 immunostaining (D). Critical Reviews in Oncology / Hematology  , DOI: ( /j.critrevonc ) Copyright © 2014 Elsevier Ireland Ltd Terms and Conditions

3 Fig. 2 Flowchart of eligible studies.
Critical Reviews in Oncology / Hematology  , DOI: ( /j.critrevonc ) Copyright © 2014 Elsevier Ireland Ltd Terms and Conditions


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