1. ELIXIR Core Data Resources and Deposition Databases

2. Open data requires infrastructure

3. Data infrastructure for the next 20 years

4. Why do we need indicators?
Life Science Community
Science policy actions: towards long term preservation of, and access to, biological data
Build trust in a broad user base, in particular for new or occasional users
Resource managers
Build capacity across partners regarding effectiveness and excellence in resource management
Indicators allowing life-cycle management based on objective criteria

5. What are ELIXIR Core Data Resources?
A set of data resources that are of fundamental importance to the broad life science community and the long-term preservation of biological data
They provide complete collections of generic value to life science, and show high levels of usage, scientific quality and service

6. Indicators that support decision making
A carefully chosen set of indicators, reflecting the multiple facets of bioinformatics resources
Impact
Scientific focus
Indicators that support decision making
Scientific impact
Community
Legal &
funding infrastructure
Quality
Scientific focus and quality of science
Community served
Quality of service
Legal and funding infrastructure and governance
Impact and translational stories

7. 1. Scientific focus and quality of science
Measuring what? Inherent scientific quality of the resource, its uniqueness and comprehensiveness
Indicators:
Archives vs knowledge bases
Scope statement: scientific coverage and comprehensiveness
International dimension
Staff effort: including curation effort

8. 2. Community served Community Measuring what? Usage of the resource
Indicators:
Overall usage: access via web browser and other methods
Potential usage
Usage in research as measured through citation in the literature: the resource name, data of a resource
Dependency of other resources

9. 3. Quality of service Quality
Measuring what? Service levels and reliability
Indicators:
Use of persistent and unique identifiers
Data throughput: number of entries, depositions
Technical performance: uptime, response time
Use of community-recognized standards for (meta)data
Links to documentation of provenance
Data availability - access services and formats
Customer service: helpdesk, user feedback, training activities

10. Legal & funding infrastructure
4. Legal and funding infrastructure,
and governance
Legal & funding infrastructure
Measuring what? Soundness of the legal, funding
and governance structure guaranteeing its long-term stability
Indicators:
Scientific Advisory Board
Legal framework supporting Open Science
Privacy policy
Ethics policy
Sustainable support and funding

11. 5. Impact and translational stories
Measuring what? Is the resource meeting its objective of fulfilling a specific need of the scientific community
Indicators:
Counterfactual analysis
Accelerating science
Translational data

12. Benchmarking FAIR against our indicators
Core resources are
Findable
Accessable
Interoperable
Reusable
FAIR Principles
Core Data Resource Indicators
1 Science
2 Community
3 Service
4 Governance
5 Impact a b c d e f g
Findable: F1 F2 F3 F4
Accessible: A1
A1.1
A1.2 A2
Interoperable: I1 I2 I3
Re-usable: R1
R1.1
R1.2
R1.3
Core resources address scientific need, community and impact
Core resource indicators support decisions on value

13. For more details

14. Process to identify ELIXIR Core Data Resources
ELIXIR Scientific Advisory Board
Advises on the process
Comments the overall list of ELIXIR CDRs
ELIXIR Nodes
ELIXIR Hub
ELIXIR Director
Heads of Nodes Committee
Submit Case Document(s)
Hub
Checks application
Director
Informs HoNs Committee of applications
Establishes the list of ELIXIR Core Data Res.
Reviews and adds to the list
Panel of
independent experts
Review the applications

15. Themes arising, for discussion
Scope
Breadth of coverage and community served
Knowledgebases and deposition databases (archives)
Nested resources
When many resources coordinate under an “umbrella” resources
e.g. InterPro Consortium (14 protein family databases)
Licensing and reuse
“Terms of use” “Public domain”
Creative commons licenses that support open science: CC0, CC-BY, CC-BY-SA
Other

16. Initial set of Core Data Resources
ArrayExpress
ChEBI
ChEMBL
EGA
ENA
Ensembl
Ensembl Genomes
Europe PMC
Human Protein Atlas
The IMEx Consortium (IntAct and MINT)
InterPro
PDBe
PRIDE
STRING db
UniProt

17. Emerging requirement: Deposition Databases
To respond to funders and journals regarding data management policies and plans
An ELIXIR Deposition Database is defined as
being part of an ELIXIR Node portfolio of services
accepting deposition of experimental data from an international community of researchers beyond the funding envelope of the database itself
meeting the technical quality and governance criteria expected of ELIXIR Core Data Resources, but may be at an earlier stage of development, meeting an emerging scientific requirement, or may be narrower in scope.

18. Initial set of ELIXIR Deposition Databases
ArrayExpress
BioModels
EGA
ENA
IntAct
MetaboLights
PDBe
PRIDE
BioSamples
BioStudies
EVA
EMDB

19. Summary & Future Another round of CDR selection in 2018
CDR Forum within Data Platform
realise the shape of the data infrastructure
publication on vital statistics
Feeding into the Global Data Resource Coalition