1. DNA Organization and Aging
Eukaryotic DNA Organization
Prokaryotic DNA organization
Telomeres and Aging – Fountain of Youth?

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3. Eukaryotic DNA Organization
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This allows us to fit 6 feet of DNA in each cell!

4. Prokaryotic DNA organization
The bacterial DNA consists almost entirely of one chromosome that is commonly circular
It can be linear in some cases

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6. Telomeres
However, DNA polymerase needs a starting point therefore, it uses a primer. What ………….

7. ___________
Therefore it cannot synthesis the end piece of DNA.
That section is lost to both the parent and replicated strand.

8. Telomeres
The loss of DNA during every cycle of replication causes chromosomes to continually shorten and can lead to the loss or damage of important genes.
To prevent the loss of essential coding regions of DNA, zones of repetitive, ……………..
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11. If chromosomes were not capped by telomeres, a small portion of a gene near the end of a chromosome could be lost every time DNA replication occurred.
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After many DNA replications, the telomeres are completely lost and therefore no ………….

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