1. Copyright © 2009 Pearson Education, Inc. Chapter 10 DNA Replication and Recombination

2. Copyright © 2009 Pearson Education, Inc. Chapter Contents 10.1DNA Is Reproduced by Semiconservative Replication 10.2DNA Synthesis in Bacteria Involves Five Polymerases, as well as Other Enzymes 10.3Many Complex Tasks Must Be Performed during DNA Replication 10.4A Summary of DNA Replication in Prokaryotes 10.5Replication in Prokaryotes Is Controlled by a Variety of Genes Continued

3. Copyright © 2009 Pearson Education, Inc. 10.6Eukaryotic DNA Synthesis Is Similar to Synthesis in Prokaryotes, but More Complex 10.7Telomeres Provide Structural Integrity at Chromosome Ends but are Problematic to Replicate 10.8DNA Recombination, Like DNA Replication, Is Directed by Specific Enzymes 10.9Gene Conversion Is a Consequence of DNA Recombination

4. Copyright © 2009 Pearson Education, Inc. The complementarity of DNA strands allows each strand to serve as a template for synthesis of the other. (Figure 10.1) Section 10.1: DNA Is Reproduced by Semiconservative Replication

5. Copyright © 2009 Pearson Education, Inc. Three possible modes of DNA replication are possible: conservative semiconservative dispersive (Figure 10.2) Section 10.1

6. Copyright © 2009 Pearson Education, Inc. Figure 11.2

7. Copyright © 2009 Pearson Education, Inc. The Meselson-Stahl experiment demonstrated that: DNA replication is semiconservative each new DNA molecule consists of one old strand and one newly synthesized strand (Figure 10.3 and Figure 10.4) Section 10.1

8. Copyright © 2009 Pearson Education, Inc.

10. The Taylor-Woods-Hughes experiment demonstrated that DNA replication is semiconservative in eukaryotes (Figure 10.5) Section 10.1

11. Copyright © 2009 Pearson Education, Inc.

14. DNA replication begins at the origin of replication and is bidirectional rather than unidirectional (Figure 10.6). Section 10.1

15. Copyright © 2009 Pearson Education, Inc. A replicon is the length of DNA that is replicated following one initiation event at a single origin. Section 10.1