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Structure Of Adenine.

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Presentation on theme: "Structure Of Adenine."— Presentation transcript:

1 Structure Of Adenine

2 Structure of guanine

3 Cytosine

4 Thymine

5 Uracil

6 Adenine nucleoside and nucleotide

7 Pyrimidine nucleoside

8 Primary structure of DNA

9 Secondary Structure of DNA

10 Secondary structure of DNA

11 Syn and anti form of nucleoside

12 FORCES THAT STABILIZE NUCLEIC ACID STRUCTURES
SUGAR-PHOSPHATE CHAIN CONFORMATIONS BASE PAIRING BASE-STACKING,HYDROPHOBIC IONIC INTERACTIONS

13 BASE-PAIRING WATSON-CRICK GEOMETRY HOOGSTEEN GEOMETRY
THE A-T PAIRS USE ADENINE’S N1 AS THE H-BOND ACCEPTOR HOOGSTEEN GEOMETRY N7 IS THE ACCEPTOR SEEN IN CRYSTALS OF MONOMERIC A-T BASE PAIRS IN DOUBLE HELICES, W-C IS MORE STABLE ALTHOUGH HOOGSTEIN IS MORE STABLE FOR A-T PAIRS, W-C IS MORE STABLE IN DOUBLE HELICES CO-CRYSTALLIZED MONOMERIC G-C PAIRS ALWAYS FOLLOW W-C GEOMETRY THREE H-BONDS

14 IN MOST DOUBLE-HELICAL STRUCTURES, ALL BASES IN ANTI FORM

15

16 Hydrogen bonding between A and T

17 Hydrogen bonding between G and C


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