1. Primary Hepatic Malignant Fibrous Histiocytoma Mimicking Hepatocellular Carcinoma: Report of Two Cases with Immunohistochemical Detection of Ezrin, and Ultrastructural and K-ras Mutation Analysis 
Phui-Ly Liew, Ming-Te Huang, Sey-En Lin, Hsin-An Chen, Chih-Hsiung Wu, Wei-Hwa Lee 
Journal of Experimental & Clinical Medicine 
Volume 4, Issue 3, Pages (June 2012)
DOI: /j.jecm
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2. Figure 1
CT scan of case 1. A lobulated mass (16×15×13cm3) occupying segments 4, 5, and 8 of liver, with an initial peripheral and gradual fill-in enhancement pattern, and central areas of necrosis were found. Tumor had ruptured at its lateral margin, with blood clot in right perihepatic space. CT=computed tomography.
Journal of Experimental & Clinical Medicine 2012 4, DOI: ( /j.jecm )
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3. Figure 2
CT scan of case 2 showed a solitary mass (3×2.5×1cm3) with irregular margin in segment 6 of liver, with a peripheral enhancement pattern and central area of necrosis. CT=computed tomography.
Journal of Experimental & Clinical Medicine 2012 4, DOI: ( /j.jecm )
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4. Figure 3
Macroscopic findings of the cut surface of the tumor in (A) case 1 and (B) case 2.
Journal of Experimental & Clinical Medicine 2012 4, DOI: ( /j.jecm )
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5. Figure 4
Microscopic features of hepatic MFH in (A) case 1 and (B) case 2. The storiform–pleomorphic growth patterns were similar in both cases (hematoxylin and eosin staining, original magnification in A and B, ×100). MFH=malignant fibrous histiocytoma.
Journal of Experimental & Clinical Medicine 2012 4, DOI: ( /j.jecm )
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6. Figure 5
Ezrin immunoexpressions in tumor cells from (A) case 1 and (B) case 2. Immunohistochemical staining with hematoxylin counterstained was shown (original magnification in A and B, ×400).
Journal of Experimental & Clinical Medicine 2012 4, DOI: ( /j.jecm )
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7. Figure 6
Representative electron microscopic images of the tumor from (A) case 1 and (B) case 2. Fibroblast-like cells with prominent cytoplasmic rough endoplasmic reticulum and histiocyte-like cells with prominent lysosomes were noticed (original magnification in A, ×5000; in B, ×12,000).
Journal of Experimental & Clinical Medicine 2012 4, DOI: ( /j.jecm )
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8. Figure 7
The K-ras exon 2 codon 12 or 13 mutation analysis is not detectable.
Journal of Experimental & Clinical Medicine 2012 4, DOI: ( /j.jecm )
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