1. WFH GAP Program
Alain Weill, WFH President
March 5, 2017

2. GLOBAL ALLIANCE FOR PROGRESS (GAP) Program
Flagship WFH healthcare development project
Launched in 2003
Foster partnership between government, healthcare providers and patients
Develop sustainable national care programs
Multi-sponsored program 2

3. GAP: 10 YEAR STRATEGIC GOALS (2013-2022)
Second Decade of GAP
Identifying an additional 50,000 people with inherited bleeding disorders by 2022, with 50% of them living in the world’s poorest regions
Results to date
30,296 have been identified globally
Including 6,852 from the poorest countries 3

4. GAP Second Decade: Components
Tier 1
Continue successful strategy of GAP
Tier 2
Advance achievements post gap
Tier 3
Assist countries with mid-level treatment
As we continue to serve new countries under the GAP program, we will also make efforts to advance further the gains in those countries that have already completed GAP and also start work in countries with mid level treatment so as to try to get them to the next level of care.
In this phase we will also enhance data collection process as well as extend the focus of diagnosis and treatment to patients with inhibitors, VWD, the rarer coagulation factor deficiencies, platelet disorders and with a special attention also to women with these disorders. 4

5. GAP Second Decade: Components
Full-GAP Program: Continuation of current GAP working on all 6 pillars of WFH Development Steps Model
Post-GAP Program: Post-GAP countries which would benefit from additional support in advancing a National Country Program, building up on GAP Phase 1 achievements or improving sustainability of Phase 1
Mid-Level GAP Program: Intermediate level countries which need help in moving forward to the next level of care 5

6. WFH DEVELOPMENT MODEL
A step-by-step process to reach sustainable care across six distinct but interrelated pillars
Improve medical expertise and increase accurate laboratory diagnosis through training
Build a strong national patient organization
through capacity
Achieve government support through advocacy
Increase access to safe
treatment products
Track national
demographic data
Improve care delivery
The WFH works globally to close the gap in care between those who receive proper treatment and those who do not
A step-by-step process to bring about sustainable care across six distinct but interrelated pillars
INCREASING ACCURATE LABORATORY DIAGNOSIS
IMPROVING MEDICAL EXPERTISE AND CARE DELIVERY THROUGH TRAINING
BUILDING A STRONG NATIONAL PATIENT ORGANIZATION THROUGH CAPACITY
ACHIEVING GOVERNMENT SUPPORT THROUGH ADVOCACY
INCREASING ACCESS TO SAFE TREATMENT PRODUCTS
TRACKING NATIONAL DEMOGRAPHIC DATA 6

7. GAP PARTICIPATING COUNTRIES: 2003-2016
Russia
Belarus
Serbia
Georgia
China
Moldova
Azerbaijan
Jordan
Armenia
Tunisia
Lebanon
Turkey
Vietnam
Mexico
Honduras
Morocco
Egypt
Syria
Thailand
Philippines
Colombia
Algeria
Ecuador
Peru
Brazil
South Africa
TOTAL: 26 countries / 31 programs 7

8. GAP Overall achievements: 2003-2016
81,212 new PWH diagnosed/registered globally (end 2015)
26 countries enrolled; 31 multi-year national bleeding disorder care development plans drawn up
19 GAP MoU signed
29,247 PWH / 4,824 VWD / 3,160 RBD diagnosed in GAP countries
16,449 new patients, family members, and (NMO) board members trained / 23,366 medical professionals trained
Treatment product access: Over billion IUs purchased 8

9. GAP ACHIEVEMENTS: January - DECEMBER 2016
Overall Results
12 active countries / closing of GAP South Africa and GAP Moldova (end 2015)
4 new GAP countries in 2016: Vietnam (T1), China (T2), Morocco (T2), and Turkey (T3)
2 GAP MoUs signed (Jordan, Vietnam) and continued discussions and negotiations on other MoUs (Honduras, Serbia)
Continued collaboration following signed MoUs (Algeria, Colombia, Egypt and Morocco)
462 new patients with hemophilia, 157 with VWD, 134 with rare clotting factor deficiencies diagnosed / registered in GAP countries
Over 710 million IUs increase in product supply 9

10. TOTAL: 13 2017 gap COUNTRY PROGRAMS Europe Serbia Turkey Americas Asia
Colombia
Honduras
Brazil
Uruguay (NEW Tier 3)
Asia
China
Vietnam
Malaysia (NEW Tier 3)
Middle East
Egypt
Jordan
Morocco
Tunisia (NEW Tier 2)
TOTAL: 13 10

11. GAP VIETNAM (TIER 1 –FULL-GAP PROGRAM)
Population (2014): 93,421,835
GNI per capita (2015): 1,980 (US$)
Public Health expenditure,(% of GDP) (2014): 3.8
Expected number of people with hemophilia / prevalence: 6,213
Confirmed number of people with hemophilia (2014): 2,373
Factor VIII usage (2014): IU per capita
*Population, Confirmed number of PWH & Factor VIII usage : Global Survey 2014
*GNI per capita & Public Health expenditure: World Bank

12. GAP MOU signing ceremony: September 21,2016

13. GAP planning visit – February 13-14, 2017
During February 13-14, 2017, a visit was organized in Vietnam to develop a detailed action plan for the GAP Program.

14. VIETNAM DEVELOPMENT PLAN: MAIN OBJECTIVES
Government support for a national hemophilia care program
Strengthening exiting network of 7 hemophilia treatment centres
Development of medical expertise of HCPs in selected 7 HTCs
Increase the supply of factor concentrates and increase factor concentrates access for patients
Expand NMO and increase its lay leadership and number of active volunteers
Support development and implementation a national registry

15. Support to Vietnam through other programs
Vietnam – Ireland HOT Twinning Program,
Hanoi (NIHBT) – Melbourne (Alfred Hospital) HTC Twinning Program
Participation in the WFH Global NMO Training, international meetings, and congresses
WFH Humanitarian Aid Program donations (3 M ius in 2016)
Improve laboratory diagnosis standards through participation in IEQAS
Training of healthcare professionals through WFH IHTC Fellowship Program
Participation in the ASEAN Hemophilia Network meetings/ workshops

16. THANK YOU