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The Soccer Mom: A Case Study on the Nervous System by Jennifer Bolognese, Misti Coronel, Anita Intorre, and Phil Stephens; Biology Department Villanova University Modified Image Credit Description: Rhagoletis pomonella (male and female apple maggot flies) Source: Author: Jack Kelly Clark Licensing: Photo of Rhagoletis pomonella from UC IPM Pest Management Guidelines: Apple, UC ANR Publication Used with permission from University of California Statewide IPM Program (
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1. What problems does Phyllis seem to be experiencing?
2. Which one of these could be caused by dehydration? Lack of concentration Forgetful Fainting
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3. What is the evidence that there is more going on than just dehydration? A) she has periods of time she can’t remember B) she is also having trouble concentrating at work C) she drank fluid and doesn’t feel better D) There isn’t any evidence.
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4. What new signs or symptoms has Phyllis revealed to her doctor?
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5. Which of these symptoms could be attributed to depression
5. Which of these symptoms could be attributed to depression? A) fingers go numb B) coordination off C) fainting D) tired
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6. Based on what we have learned about neurotransmitters, which two are thought to be involved in depression? A) dopamine and serotonin B) ACh and dopamine C) serotonin and histamine D) endorphins and histamine
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7. What body systems could have caused her grandfather to be in a wheelchair? A) integumentary B) muscular C) skeletal D) nervous E) B, C, and D F) all of the above
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8. If you were in Dr. Warner’s position, what tests might you suggest to determine what is going on?
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9. Talk with a partner and fill in the flow chart diagram using the following terms:
adjacent threshold axon hillock synapse excitatory postsynaptic potential nodes of Ranvier sodium
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10. What type of cell is myelin? A) neuron B) glial
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11. What is the function of myelin in nerve cells
11. What is the function of myelin in nerve cells? A) decrease the speed of nerve transmission B) increase the speed of nerve transmission C) generate action potentials D) pass electrical signal from cell to another cell E) increase the magnitude of the action potential
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12. In myelinated axons, where are action potentials generated
12. In myelinated axons, where are action potentials generated? A) Node of Ranvier B) cell body C) dendrites D) underneath the myelin 13. Where, then, are voltage gated sodium channels concentrated in myelinated axons? A) Node of Ranvier B) cell body C) dendrites D) underneath the myelin
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Read Part III
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14. What happens to myelin in people who suffer from multiple sclerosis? A) breaks down B) builds up too much C) seals up Node of Ranvier 15. Why is there an elevated level of myelin basic protein in the cerebrospinal fluid?
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16. What would be the effect on action potential conduction at a region of axon where the disease had its effect? A) increase action potential conduction B) decrease action potential conduction C) no change to action potential conduction 17. What effect would this have on the coordination of movements if this took place in areas involved in motor control of finger movements?
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Interferon beta: decreases your immune response
Corticosteroids: reduces inflammation and decreases severity of attack
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