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Antinociceptive, Anti-inflammatory Effects and Acute Toxicity of Aqueous and Ethanolic Extracts of Myrtus communis L. Aerial Parts in Mice  Hossein Hosseinzadeh,

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Presentation on theme: "Antinociceptive, Anti-inflammatory Effects and Acute Toxicity of Aqueous and Ethanolic Extracts of Myrtus communis L. Aerial Parts in Mice  Hossein Hosseinzadeh,"— Presentation transcript:

1 Antinociceptive, Anti-inflammatory Effects and Acute Toxicity of Aqueous and Ethanolic Extracts of Myrtus communis L. Aerial Parts in Mice  Hossein Hosseinzadeh, Mohammad Khoshdel, Maryam Ghorbani  Journal of Acupuncture and Meridian Studies  Volume 4, Issue 4, Pages (December 2011) DOI: /j.jams Copyright © Terms and Conditions

2 Figure 1 Effect of the aqueous extract of M communis L. aerial parts and morphine on the pain threshold of the mice in the hot-plate test. The effect of naloxone on the aqueous extract of M communis L. is also shown. Each point represents the mean±SEM of reaction time for n=8 experiments on the mice. *p<0.05, **p<0.01, ***p<0.001, Tukey-Kramer test. Journal of Acupuncture and Meridian Studies 2011 4, DOI: ( /j.jams ) Copyright © Terms and Conditions

3 Figure 2 Effect of the ethanolic extract of M communis L. and morphine on the pain threshold of the mice in the hot-plate test. The effect of naloxone on the ethanolic extract of M communis L. is also shown. Each point represents the mean±SEM of reaction time for n=8 experiments on mice. *p<0.05, **p<0.01, ***p<0.001, Tukey-Kramer test. Journal of Acupuncture and Meridian Studies 2011 4, DOI: ( /j.jams ) Copyright © Terms and Conditions

4 Figure 3 Effect of naloxone on the antinociceptive effect of the aqueous extract of M communis L. on the acetic acid-induced writhing test in mice. Values are the mean±SEM for 6 mice. All groups significantly decrease the number of writhes in 10min; naloxone could not inhibit this effect. *p<0.05, compared with control. Tukey-Kramer test. Journal of Acupuncture and Meridian Studies 2011 4, DOI: ( /j.jams ) Copyright © Terms and Conditions

5 Figure 4 Effect of naloxone on the antinociceptive effect of the ethanolic extract of Myrtus communis L. on the acetic acid-induced writhing test in mice. Values are the mean±SEM for 6 mice. All groups significantly decreased the number of writhes in 10min; naloxone could not inhibit this effect. *p<0.05, compared with control, Tukey-Kramer test. Journal of Acupuncture and Meridian Studies 2011 4, DOI: ( /j.jams ) Copyright © Terms and Conditions


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