1. Impact of Diabetic Retinopathy on Vulnerability of Atherosclerotic Coronary Plaque and Incidence of Acute Coronary Syndrome 
Osamu Kurihara, MD, Masamichi Takano, MD, Kyoichi Mizuno, MD, Yusaku Shibata, MD, Masato Matsushita, MD, Hidenori Komiyama, MD, Masanori Yamamoto, MD, Katsuhito Kato, MD, Ryo Munakata, MD, Daisuke Murakami, MD, Kentaro Okamatsu, MD, Noritake Hata, MD, Yoshihiko Seino, MD, Wataru Shimizu, MD 
American Journal of Cardiology 
Volume 118, Issue 7, Pages (October 2016)
DOI: /j.amjcard
Copyright © 2016 Elsevier Inc. Terms and Conditions

2. Figure 1
Representative angioscopy image of patient with DR. No angiographic stenosis was observed in the right coronary artery (Panel A), whereas an intramural red thrombus was observed at the middle site (Panel C) and 3 yellow plaques were identified on angioscopy (Panels B to D). The yellow intensity of these plaques was defined as grades 2, 3, and 2, respectively. Significant stenosis was not observed in the left circumflex artery (Panel E), whereas 2 yellow plaques were defined as grades 2 and 1, respectively (Panels F and G). A 90% stenosis was identified on angiography in the proximal part of the left ascending artery (Panel H). On angioscopy, 2 yellow plaques were identified on angioscopy in the proximal and middle parts of the left ascending artery (Panels I and J). The yellow intensity of these plaques was defined as grades 2 and 3, respectively. In this case, the average NYP was 2.33 (7 yellow plaques in 3 vessels), the MYG was 3.
American Journal of Cardiology  , DOI: ( /j.amjcard )
Copyright © 2016 Elsevier Inc. Terms and Conditions

3. Figure 2
Comparisons of coronary atherosclerosis on angioscopy. The NYP per vessel (A) and the MYG (B) are shown. Error bars indicate 95% CIs. Coronary arteries in patients with DR had a significantly greater NYP (1.26 ± 0.77 vs 2.08 ± 1.01, p = 0.002) and a significantly higher MYG (1.90 ± 0.82 vs 2.40 ± 0.74, p = 0.044) than those in patients without DR.
American Journal of Cardiology  , DOI: ( /j.amjcard )
Copyright © 2016 Elsevier Inc. Terms and Conditions

4. Figure 3
Cumulative incidences of ACSs in relation to the presence or absence of DR. Cumulative incidences of ACS over mean 7.1 years of follow-up were plotted using Kaplan–Meier curves. The log-rank test showed that the DR group had a significantly higher incidence of ACS than the non-DR group (p = 0.004).
American Journal of Cardiology  , DOI: ( /j.amjcard )
Copyright © 2016 Elsevier Inc. Terms and Conditions