1. Pharmacy Technician
Compounding

2. Compounding
Extemporaneous compounding is the on-demand preparation of a drug product according to a physician’s prescription to meet the unique needs of an individual patient.
Definition: the preparation, mixing, assembling, packing and labeling of a drug device
Compounding is regulated by the State Boards of Pharmacy & the US Pharmacopeia

3. Reasons for Compounding
Pediatric patients requiring diluted adult strengths of drugs
Patients needing an oral solution or suspension of a product that is only available in another form
Patients with sensitivity to dyes, preservatives or flavoring agents found in commercial formulations

4. Reasons continued…
Dermatological formulations with fortified or diluted concentrations of commercially available products
Specialized dosages for therapeutic drug monitoring
Care for hospice patients in pain management
Compounding for animals

5. Technicians are increasingly involved in compounding, under supervision of a pharmacist.

6. Compounding Regulations
Personnel
Facilities & Equipment
Ingredient Standards
Quality Assurance and Quality Control

7. Packaging and storing
Documentation & Record Keeping

8. Compounding Considerations
Is there a commercial product available?
Is the pharmacist qualified to compound?
Determine a preliminary procedure.

9. MEASURE MIX MOLD PACKAGE
4 step process
MEASURE MIX MOLD PACKAGE

10. Equipment Balance Spatulas Weighing papers & Weighing Boats
Electronic, Class Aa
Spatulas
Weighing papers & Weighing Boats
Mortars and Pestles

11. Volumetric (liquid) Equipment
Graduated Cylinders
Volumetric Flasks
Pipets
Single volume, calibrated
Syringes
Oral
Droppers

12. Mixing Solids & Semisolids
Mixing Tablets
Ointment Slabs
Levigation
Hot plates

13. Compounding Principles for Dosage Forms
Aqueous solutions
Nonaqeuous solutions
Suspensions
“Flavor”
Emulsion
Ointment (2 types)
Suppository bases
Capsules