1. Calidad y Trazabilidad Leica XL SEAP 2017 - Curso de Preanalitica
24 Febrero 2017

2. Leica Biosystems
Our Mission Advancing cancer diagnostics, Improving lives

3. Because time is of the essence…
Consult
Biopsy
AP Lab
Diagnosis
Consult
Don’t wait another day
Aligning and integrating the workflow to enable same day diagnosis

4. Striving towards Vision24
Enabling clinicians to efficiently provide patients a highly confident diagnosis within 24-hours from biopsy

5. Beginning to end integration
A holistic system-wide approach to the lab
Service & Support from beginning to end
Biopsy
Preanalytics
Primary Staining
IHC/ISH
Imaging
Diagnosis
1. Only company to own the workflow from biopsy to diagnosis
3. Enabling control of the lab through IT solutions
2. Dedicated consumables for our instruments

6. CEREBRO and APiQ software solutions
Unleashing productivity and innovation
Improved sample tracking and traceability with CEREBRO
APiQ unified device management across the lab
Manage inventory and control costs with APiQ
Data-driven decisions to improve control and productivity

7. Protect Their Health, and Your Reputation
Scanning the item ID actively verifies critical case details and securely links each patient to all case items
Active verification warns if operator is linking wrong slide or cassette to a case
Documenting the process and chain of custody
Track steps as the sample moves through the laboratory
Increasing accountability
Each scan records who, what, when and where

8. Impact of Sample Tracking
450
Asset Tracking
400
Wrong Stain
350
Slide Missing (Recut)
Slides Mislabelled
300
Cassettes Missing
Cassette Mislabelled
250
No entry of Cassette
200
150
100 50
Nov 08
Dec 08
Jan 09
Feb 09
Mar 09
Apr 09
May 09
Jun 09
Jul 09
Aug 09
Sep 09
Oct 09
Nov 09
Dec 09
Jan 10
Feb 10
Mar 10
Apr 10
May 10
Jun 10
Jul 10
Aug 10
Source: John H Sinnard, MD, PhD. Pathology Informatics, Yale School of Medicine, 2010, Pathology Informatics, “Histology asset tracking dashboard: Real-time monitoring and dynamic work lists” , pp 17-18

9. Impact of Sample Tracking – Reduced Risk
Before
CEREBRO
3 months using
CEREBRO
Accessioning
Grossing
Embedding
6 months using
CEREBRO
Microtomy
Send out
Error risk assessment
Since installing CEREBRO (Dec 2012), Pathlab laboratories has reported no incidents or issues. They attribute this great result to the consistently great safety and quality control data provided by the CEREBRO system. These results are exceptional in comparison to industry averages presented in the study by Nakhleh et al This level of performance is achieved with rigorous procedures and very high standards of quality tracking.
Source: Corinne Hill, BSc MSc, Lead for Histology from Pathology Associates Ltd, Pathology Leaders Webinar: Patient Specimen Safety in the Modern Histology Lab, September , Online

10. Powerful, Yet Easy to Use and Learn
Add cassettes or slides
Edit Case
Add Note
Add no. of Tissue
Un-use and re-use item
Print item
Counters for grossed and all samples
Case information
Printed and loaded cassette
Container for grossed samples
Unread note attached to the cassette
Grossed sample
Container for loaded cassettes
Unloaded routine slide
Counters showing loaded and all cassettes
Unloaded charged slides for advanced staining

11. Highly Visual and Informative

12. Increased Flexibility
UNIVERSAL
ACCESSIONING
GROSSING
TISSUE
EMBEDDING
SECTIONING
STAINING
SEND-OUT
REPORTING
Extend tracking to any corner of your laboratory with the Universal workstation. Now you can track specimens at archival, cryosectioning and many other operations
PROCESSING
ADDITIONAL FIXATION
DECALCIFICATION
FROZEN SECTION
SAMPLE STORAGE
SLIDE ARCHIVAL
TRACKING REFFERED CASES
DELIVERY TO PATHOLOGIST
Automated stainers
(BOND, H&E, Special)
Manual staining and
non-connected instruments

13. Configure CEREBRO to Your Tracking Needs
Skip existing or add new tracking steps
Accession
Gross
Decal
Process
Embed
Section
Stain
Release
Diagnose
Archive
Order
Scan &
track
Print
Order
Scan &
Scan &
Scan &
match
track
Scan &
track
track
Print
Order
Scan &
Scan &
Scan &
Scan &
Scan &
match
track
track
track
track
Print

14. Accessioning Works seamlessly with or without LIS feed
Associate lab-specific unique ID to case
Structure cases via panels
Option to print request forms and container labels
Option to batch print slides, slide labels and/or cassettes
17” touch screen PC with keyboard and mouse, barcode scanner, label printer, choice of printing options

15. Grossing
Scan container to start printing cassettes or use batch printed cassettes
Scan cassette to verify correct “loading” of tissue
View/set the number of tissue pieces loaded
View/add notes and special instructions
Option to assign samples to temporary storage
Option to assign blocks to tissue processing basket for easy tracking of processing step
Compact 12” touch screen PC, barcode scanner, flexible mounting arm, choice of printing options

16. Tissue Processing
Scan the processor and select the processing desciption
Scan the basket to assign all cassettes to the run in one go or scan individual cassettes in or out of the run as needed
CEREBRO checks the protocol description against the cassette and warns about potential mismatch
View/add notes and special instructions
Counters to show completed/remaining work
Compact 12” touch screen PC, wireless barcode scanner, flexible mounting arm

17. Embedding Scan cassettes to embed
Number of cassettes per case displayed
View/add notes and special instructions on screen
Counters to show completed/remaining work
Work within the context of tissue processing basket
Compact 12” touch screen PC, barcode scanner, flexible mounting arm
Summary of the embedding module main features
In summary, you scan your cassettes to embed. The number of cassettes for that case is displayed with any associated notes or instructions. A counter shows that progress of that case through embedding. This workflow gives security to confirm that you have the correct sample.

18. Sectioning
Scan cassette to start printing slides (or slide labels) or use batch printed ones
Scan slide to verify correct tissue “loading”
View/add notes, special instructions and number of tissue pieces loaded
Counters show completed/remaining work
Option to assign sectioned blocks to temporary storage
Option to assign slides to rack for tracking of manual staining step
Compact 12” touch screen PC, barcode scanner, flexible mounting arm, choice of printing options

19. Staining with Connected Instruments
Connect CEREBRO to Leica BOND and 3rd party instruments
Eliminate redundant data entry and related errors
No re-labeling or sorting needed
Instrument uses the barcode to link it to the staining information from CEREBRO
Skilled staff freed for more valuable tasks
Maximize your laboratory’s workflow efficiency
Customizable uni- or bi-directional HL7 messaging interface based on available instrument interfacing options

20. Staining Station Track manual staining and non-connected instruments
Scan a tray to assign all slides to the run, alternatively scan individual slides in or out of the run as needed
CEREBRO checks the protocol assignment against the slide and warns of any potential mismatch
View/add notes and special instructions
Counters show completed/remaining work
Compact 12” touch screen PC, wireless barcode scanner, flexible mounting arm

21. Send-out Visual representation of slide status within a case
Rapid assignment to a pathologist
Simultaneous slide release across multiple cases
View/add notes and special instructions
Use case history for troubleshooting
17” touch screen PC with keyboard and mouse, barcode scanner, flexible mounting arm
Summary of Send-Out feature set.
In summary, there is strong visual representation of slide status within a case, rapid assignment of cases to a pathologist, and send out across multiple cases, including partial cases.
That concludes the overview of the 5 key clients for the CEREBRO product, moving through the workflow from end to end, accessioning to sign out.

22. Universal Station Track virtually any step in the workflow
Potential application include:
Tracking non-standard workflow such as additional fixation or decalcification
Sample storage and disposal after grossing
Block and slide archival
Slides and blocks sent for referral
12” compact touch screen PC, barcode scanner, flexible mounting arm

23. Administration System configuration module
Tests, test panels
Tissue, procedure, section, processing descriptions
Cassette and slide types
Containers and locations
Label designer
Users and access rights
LIS Connectivity configuration
CEREBRO admin, laboratory/IT admin.
Only a single instance is required
Included in every installation 58

25. Questions?