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Antibiotics By Alaina Darby
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Which of the following is a term that would not apply to the treatment of a virus-caused condition?
Chemotherapy Antibiotic Antimicrobial Selective toxicity b
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Which of the following describes post-antibiotic effect?
Suppression of bacterial growth after ceasing antibiotic administration Suppression of bacterial growth after ceasing antibiotic administration and concentration is below MIC Bacterial regrowth after ceasing antibiotic administration Bacterial regrowth after ceasing antibiotic administration and concentration is below MIC b
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Antibiotic specificity and spectrum
Which of the following is the most important factor in determining antimicrobial therapy? Antibiotic specificity and spectrum Bactericidal vs bacteriostatic function Diagnosis of infecting organism Post antibiotic effect c
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Less alteration of GI microflora Aid in organism identification
Why might one choose erythromycin over an antibiotic like metronidazole that has a broader spectrum? Less alteration of GI microflora Aid in organism identification Target a specific area of the body Decrease the MIC a
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Which of the following describes the latency period?
Time from administration until the drug kills all bacteria in a cidal drug Time from administration until the drug begins to inhibit bacterial multiplication in a cidal drug Time from administration until the drug begins to reduce the number of pathogens in a cidal drug Time from administration until the drug begins to reduce the number of pathogens in a static drug c
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Neither bactericidal or bacteriostatic
Which of the following relies upon host defenses to aid in eliminating the pathogen? Bactericidal Bacteriostatic Neither bactericidal or bacteriostatic Both bactericidal and bacteriostatic d
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Reduced number of organisms More effective
What would not be a reason for choosing a bactericidal agent over a bacteriostatic agent? More rapid acting Reduced number of organisms More effective Effects without maintaining MIC c
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Which of the following cases would not require a bactericidal agent?
Bacterial endocarditis Pertussis Meningitis Transplant patient b
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Which of the following exhibits no post- antibiotic effect?
Aminoglycosides Fluoroqinolones Clindamycin Vancomycin d
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Which of the following exhibits no post-antibiotic effect?
Time-dependent Concentration-dependent Time-dependent and concentration-enhanced Concentration-dependent and time-enhanced a
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Which of the following is a protected site into which antibiotic will not be readily available?
Bladder Kidney Prostate Lungs c
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Metabolism and excretion Route of administration Anaerobic conditions
Which of the following is not a major concern when selecting an antibiotic for its concentration at the site of infection? Patient compliance Metabolism and excretion Route of administration Anaerobic conditions d
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Increase bactericidal activity at the same site
Which of the following would not be reason to use combination chemotherapy? Increase bactericidal activity at the same site Prevent emergence of resistant organisms Permit lower doses of the antibiotics Treat infection of unknown etiology a
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Which of the following is not an infection that is often treated with combination chemotherapy?
Tuberculosis Malaria HIV Meningitis d
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What would not be a reason to choose a single agent for therapy?
Same site toxicity Mixed bacterial infection Static plus cidal combination Increased cost b
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Which of the following is not true of superinfections?
They are due to alterations in the normal flora Incidence increases with broad spectrum agents They are a reappearance of the primary infection They appear during treatment c
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Which of the following is not true of antibiotic resistance?
Natural resistance is present before antibiotic therapy Acquired resistance is caused by the antibiotic Acquired resistance occurs in a species that was once sensitive Acquired resistance is a consequence of antibiotic therapy b
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Which of the following is not an indication for prophylaxis?
Prevent infection by a specific organism Prevent all potential secondary infections in a patient ill with other diseases Prevent infection from rupture of a viscus or a surgical procedure Prevent bacterial endocarditis or recurrence of rheumatic fever b
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Which of the following would not be true of the ideal antimicrobial?
Alkaline stable Orally absorbed Bactericidal Good distribution to bones a
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Which of the following would not be true of the ideal antimicrobial?
Readily excreted Widest spectrum possible Low MLC High tissue concentration b
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penicillins
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Which of the following do penicillins inhibit?
Joining of L-Alanine to D-Alanine Joining of L-Alanine to Glycine Joining of Glycine to D-Alanine Joining of L-Lysine to D- Alanine c
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Which of the following is effective against Treponema pallidum when given orally?
Penicillin V Nafcillin Dicloxacillin Piperacillin a
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Which of the following would be used to treat MSSA when given parenterally?
Penicillin G Penicillin V Nafcillin Oxacillin c
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Which of the following is used in pseudomonal infections?
Ticarcillin orally Ticarcillin parenterally Ampicillin orally Ampicillin parenterally b
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Which of the following is usually combined with aminoglycosides for serious infections?
Piperacillin Penicillin V Nafcillin Cyclacillin a
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Which of the following is not effective against gram negative rods?
Ampicillin Ticarcillin Cyclacillin Penicillin G d
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Which of the following is not effective against some gram negative cocci?
Ampicillin Ticarcillin Cyclacillin Penicillin G b
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Which of the following might be used in the prevention of streptococcal pharyngitis or the treatment of syphilis? Procaine penicillin G Procaine penicillin V Penicillin V Penicillin G a
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Which of the following combinations of penicillin and beta-lactamase inhibitors is given orally?
Timentin Unasyn Augmentin Zosyn c
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Which of the following is given for MSSA or anaerobe producing respiratory tract infections?
Timentin Unasyn Augmentin Zosyn c
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Which of the following is given for gram negative bacilli and includes clavulanic acid as the beta-lactamase inhibitor? Timentin Unasyn Augmentin Zosyn a
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Which of the following is true of the pharmacokinetics of penicillins?
The presence of food increases absorption Protein binding can be predicted based on chemical structure They are excreted predominantly unchanged Excretion is primarily through glomerular filtration c
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Which of the following undergoes both biliary and renal excretion?
Nafcillin Oxacillin Dicloxacillin Amoxicillin c
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Dose adjustment due to increased hepatic metabolism
Kate has decreased kidney function. Which of the following should she expect when taking penicillin? Dose adjustment due to increased hepatic metabolism Dose adjustment due to decreased hepatic metabolism Dose adjustment due to increased renal excretion Dose adjustment due to decreased renal excretion a and d
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Which of the following is not a mechanism of resistance?
Inhibition of beta-lactamases Inability of penicillins to bind to the PBP Lack of activation of autolytic enzymes Decreased penetration of penicillins to site of action a
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Which of the following would be used to treat MRSA? Tetracycline
Erythromycin Cephalosporin Vancomycin d
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Which of the following should not be used in a hypokalemic patient?
Augmentin Ampicillin Piperacillin Penicillin G c
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Which of the following may cause nausea, vomiting, and diarrhea?
Augmentin Ampicillin Piperacillin Penicillin G a
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A patient comes in with a rash three days after starting an antibiotic
A patient comes in with a rash three days after starting an antibiotic. Which antibiotic was that patient likely taking? Amoxicillin Penicillin V Oxacillin Cyclacillin a
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