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-Brain Imaging Techniques-

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1 -Brain Imaging Techniques-
CT Scan: Computerized Tomography Scan MRI: Magnetic Resonance Imaging fMRI: Functional Magnetic Resonance Imaging PET Scan: Positron Emission Tomography Scan EEG: Electroencephalogram or electrical recordings

2 CT Scans: An x-ray of the brain.
A CT scan is essentially a computerized assembly of several x-ray images taken from a series of different angles. With a CT, the resolution is much better than conventional x-rays, and the detail that can be seen is much greater. 

3 Tumor in Wernicke’s Area
        MRI is a noninvasive imaging technique that does not use x-rays.   The process involves passing a strong magnetic field through the head.  The magnetic field used is 30,000 + times that of the earth's magnetic field.  It's effect on the body, however, is harmless and temporary.  The MRI scanner can detect radiation from certain molecules, which are present in different concentrations in different tissues. 

4 P E T S C A N PET measures the emission of positrons from the brain after a small amount of radioactive isotopes, or tracers,  have been injected into the blood stream.  A common example is a glucose-relative with embedded fluor-18.   With this molecule, the activity of different regions of the brain can be measured.  The result is a three-dimensional map with the brain activity represented by colors. 

5 After Implant of Dopamine-secreting Tissue
Brain Development in First Year of Life

6 Alert Deep Sleep

7 The Evolution of the Brain

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9 Major Brain Regions: Brainstem
Pons Connects brainstem with cerebellum - Involved in arousal and sleep T h a l m u s C o r p c H y t P n M e d S i b Cerebellum Coordination of voluntary movement and sense of equilibrium C e r r

10 Major Brain Regions: Midbrain
Part of the brainstem between the hindbrain and the forebrain T h a l m u s C o r p c H y t P n M e d S i b Concerned with certain sensory processes and dopamine production Reticular Formation Regulates sleep, wakefulness & arousal Midbrain Modulates muscle reflexes, breathing & pain perception.

11 THALAMUS It relays to the cerebral cortex information received from diverse brain regions. Sort of a requisite 'last pit stop' for information going to cortex. Axons from every sensory system (except olfaction) synapse here as the last relay site before the information reaches the cerebral cortex

12 Major Brain Regions: Forebrain
Hypothalamus Regulates basic needs fighting, fleeing feeding, and fornicating T h a l m u s C o r p c H y t e b x P n M d S i Cerebrum/Cerebral Cortex Limbic System Involved in regulation of emotion, memory & motivation e

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14 Amygdala Hippocampus Involved with emotions – fear, happy, sad, angry
Emotion and Memory are closely connected. Hippocampus Is particularly involved with memory phenomena, especially with the formation of long-term memory

15 The pituitary gland may be king, but the power behind the throne is clearly the hypothalamus.

16 Major Brain Regions: Cerebral Cortex
Convoluted outer layer of cerebrum Responsible for learning, memory, thinking, sensation and consciousness

17 Structure of the Cortex
1/8th inch thick 30 billion nerve cells billion Glial cells. Each nerve cell makes 10,000 contacts each. Approximately 300 trillion connections.

18 Lobes of Cerebral Hemispheres
primary motor cortex primary somatosensory cortex primary auditory cortex primary visual cortex Temporal (“tones”) - Devoted to auditory processing Occipital (“objects”) - Devoted to visual processing Parietal (“pressure”) - Devoted to sense of touch Frontal (“??”) - Devoted to control of muscle movement, decision-making and behavioral functions (e.g., personality)

19 Motor Area Sensory Area

20 Cerebral Laterality Idea of Hemispheric Specialization
Broca’s Area Important in the production of speech Wernicke’s Area Important in the comprehension of language Idea of Hemispheric Specialization (“Left/Language & Right/Visual-Spatial”) leads to Split Brain Research by Sperry & Gazzaniga

21 Speaking the Heard Word
LANGUAGE CENTERS Disrupts Understanding Disrupts Speaking Speaking the Heard Word Speaking the Written Word Angular Gyrus Speak & Understand, Unable to Read

22 (Right side of the brain controls the Left side of the body)
Cerebral Hemispheres Corpus Callosum 200 million nerve fibers that connect Left & Right hemispheres. Allows communication between two sides of the brain. Each hemisphere’s primary connections are to the opposite side of the body (Right side of the brain controls the Left side of the body)

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24 HE ART Split Brain What effect does cutting the Corpus Callosum
Left Visual Field Right Visual Field Split Brain What effect does cutting the Corpus Callosum have on behavior? HE ART l “Say what you saw Vs. Point at what you saw” Retina Optic Chiasm Thalamus Left Visual Cortex Right Visual Cortex Corpus Callosum

25 Central Nervous System
CNS is nourished and protected by Cerebrospinal Fluid Blood-Brain Barrier Semi-permeable membrane-like mechanism that prevents some chemicals from passing between the bloodstream and the brain


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