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Annual Fall Meeting November 13, 2016

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Presentation on theme: "Annual Fall Meeting November 13, 2016"— Presentation transcript:

1 Annual Fall Meeting November 13, 2016
6:30pm Welcome J. Kirklin/M. Everitt 6:40pm Steering Committee Report M. Everitt 6:50pm DCC Update J. Kirklin/D. Naftel 7:05pm Web Based Data Entry D. Naftel 7:20pm Database Committee Report M. Richmond 7:35pm Foundation Update C. Collum/B. Wilk/R. Gajarski 7:50pm Risk Factor Model K. Schumacher 8:05pm Heart Failure Simulation B. Feingold 8:10pm iPHFR R. Gajarski 8:15pm Break 8:30pm Pedimacs Report B. Blume 8:40pm Scientific Committee Report D. Hsu 8:50pm Scientific Committee Sponsored Workshops 9:35pm New Business 9:45pm Adjourn

2 2015-2016 Scientific Committee Members
Daphne Hsu, MD Chair Elfi Pahl, MD Vice Chair/Secretary Yuk Law, MD Scientific-Steering Committee Liaison Simon Urschel, MD Co-Chair Scientific Proposal Committee Members At Large Linda Addonizio, MD Dan Bernstein, MD Ryan Butts, MD Charlie Canter, MD  Matthew Fenton, MD Steve Kindel, MD Ken Knecht, MD Bob Morrow, MD Janet Scheel, MD Rocky Singh, MD, MS James Kirklin, MD 

3 Submitted Manuscripts Status: November 2016
Topic PI/SRI Status LDS: Hemodynamics (2014) Chen Almond Submitting to British Medical Journal LDS: Surveillance Biopsies Zinn Canter Submitted both to JHLT Bacterial Infections (2015) Rostad Scheel Submitted to JHLT Induction Therapy Castleberry Urschel LDS: MATE Desai In Revisions with JHLT Cancer Recurrence Bock Bernstein Submitted to Pediatric Transplantation

4 Manuscripts in Preparation Status: November 2016
Topic PI/SRI Status VAD (2012) Dipchand Kirklin Dr. Dipchand to finalize manuscript with UAB PTLD (2014) West Feingold Dr. West to finalize manuscript with UAB MCSD Graft Failure (2015) Simmonds Addonizio Dr. Simmonds to finalize manuscript with UAB Single Ventricle in MCSD Das Canter Dr. Das to finalize manuscript with UAB Donor Crossmatch Hsu Dr. Das presenting at AHA 2016; to finalize manuscript with UAB Diabetes Post-Transplant Sparks Morrow Dr. Sparks presenting at AHA 2016; to finalize manuscript with UAB Risk Factor Wood Schumacher PHTS DCC working on analysis

5 Submitted to ISHLT 2017 Status: November 2016
Topic PI/SRI Status AE VAD (2016) Sutcliffe Bernstein PHTS DCC working on analysis Dr. Sutcliffe submitted to ISHLT 2017; to start manuscript ECMO vs VAD in Pts <10Kgs (2016) Conway Pahl Dr. Conway submitted to ISHLT 2017; to start manuscript Fontan (2013) Dykes Almond Chen Stanford working on analysis Dr. Dykes submitted to ISHLT 2017; to work on manuscript Berlin Heart (2015) Jeewa Fraser Dr. Jeewa submitted to ISHLT 2017; to start on manuscript LDR: HLA Albers Dr. Albers submitted to ISHLT 2017; to work on the manuscript CAV Insurance Pruitt Naftel Pruitt to finalize manuscript

6 Publications January 2016 - November 2016

7 Recent Publications The Journal of Thoracic and Cardiovascular Surgery, , Volume 151, Issue 1, Pages e2

8 Recent Publications Journal of Heart and Lung Transplantation, 2016: March 35 (3):

9 Recent Publications Journal of Heart and Lung Transplantation, 2016 Apr; 35 (4):

10 Recent Publications Journal of Heart Lung Transplant. 2016 Apr; 35 (4):

11 Recent Publications Journal of Heart Lung Transplant. 2016 In Press.

12 Recent Publications Journal of Heart Lung Transplant. 2016 In Press.

13 Recent Publications The Annals of Thoracic Surgery. 2016 In Press.

14 PHTS Presentations at AHA

15 New-onset Diabetes after Pediatric Heart Transplantation
AHA 2016 Poster Presentation Science and Technology Hall-Special Focus Section Monday, November 14, 2016, 2:00 pm – 3:15 pm New-onset Diabetes after Pediatric Heart Transplantation Joshua D. Sparks1, Elizabeth Pruitt,2, James K. Kirklin2, Tricia Brown1, Michael Carboni3, William Dreyer4, Thomas Ryan5, Steven Kindel6, and Robert Morrow7. 1University of Louisville, Louisville, KY; 2University of Alabama at Birmingham, Birmingham, AL; 3Duke University Medial Center, Durham, NC; 4Baylor College of Medicine, Houston, TX; 5Children’s Hospital of Wisconsin, Milwaukee, WI; 6University of Cincinnati, Cincinnati, OH; 7Children’s Hospital Dallas, Dallas, TX

16 AHA 2016 Poster Presentation Science and Technology Hall-Special Focus Section Monday, November 14, 2016, 2:00 pm – 3:15 pm Pediatric Heart Transplantation in Pre-Sensitized Recipients: A Current Perspective Bibhuti Das1, Elizabeth Pruitt2, Kimberly Molina3, William Ravekes4, Scott Auerbach5, Andrew Savage6, Leah Knox1, James Kirklin2, David Naftel2, and Daphne Hsu7 1Children’s Medical Center, University of Texas Southwestern Medical Center, Dallas, TX; 2 University of Alabama at Birmingham,, Birmingham, AL; 3 Primary Children’s Hospital, Salt Lake City, UT; 4Johns Hopkins Hospital, Baltimore, MD; 5Children’s Hospital of Colorado, Aurora, CO; 6 Medical University of South Carolina, Charleston, SC; 7The Children’s Hospital at Montefiore, Bronx, NY

17 PHTS Fall Proposals

18 Fall Proposal Review Twice yearly proposal submissions timed to the AHA and ISHLT submission dates 9 proposals reviewed by scientific proposal committee Selection being finalized and authors assigned

19 Writing Group Membership Selection
Fall Proposal Review Writing Group Membership Selection Lead author of the accepted proposal will chair the writing committee A scientific committee member will be assigned as the senior mentor to based on specific expertise. Lead author can nominate one coordinator to the writing group. If lead is a trainee, the local senior mentor will join the writing group If proposals are combined, the lead applicant of the lower ranked proposal will be offered secondary leadership The PHTS DCC will choose 2 members of the writing group Other PHTS centers (usually 2-3) will be asked to nominate a writing group member based on their previous inclusion on manuscripts # authorships/years of memberships in the PHTS Centers with the lowest number will be selected Centers who have contributed data for less than 3 years to PHTS will not be eligible

20 Fall Proposal Review Proposal Development
The project lead and PHTS scientific mentor will arrange a discussion call regarding study design, methodology and core data analysis with the PHTS statistical and support staff prior to a first writing group call. Deadlines for abstract submission and preferred journal for submission can also be discussed / established at that time. The first and senior author of the project are strongly encouraged to travel to the stats center in Birmingham, Alabama for a one day data analysis session with a concluding phone conference of the entire writing group. The goal of this meeting is to complete a large part of the analysis and optimize the analytic approach and draft the abstract for presentation of the project. Abstract presentations are reviewed by the scientific committee 2 weeks prior to presentation Manuscripts are reviewed by the scientific committee prior to submission

21 Thank You!


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