1. International Society for Heart and Lung Transplantation 2010 Annual Report International Society for Heart and Lung Transplantation: A Forum that Includes Basic Science, the Failing Heart and Advanced Lung Disease

2. About ISHLT Founded in 1981 Founded in 1981 Approximately 2500 members Approximately 2500 members Multidisciplinary (14+ disciplines) Multidisciplinary (14+ disciplines) Multinational (16+ countries) Multinational (16+ countries) Dedicated to the advancement of the science and treatment of end stage heart and lung disease Dedicated to the advancement of the science and treatment of end stage heart and lung disease International Society for Heart and Lung Transplantation: A Forum that Includes Basic Science, the Failing Heart and Advanced Lung Disease

3. ISHLT Mission Statement The International Society of Heart and Lung Transplantation is a multidisciplinary, professional organization dedicated to improving the care of patients with advanced heart or lung disease through transplantation, mechanical support and innovative therapies via research, education, and advocacy. International Society for Heart and Lung Transplantation: A Forum that Includes Basic Science, the Failing Heart and Advanced Lung Disease

4. ISHLT Goals To associate individuals interested in the fields of heart and lung transplantation, end stage heart and lung disease, and related sciences To associate individuals interested in the fields of heart and lung transplantation, end stage heart and lung disease, and related sciences To encourage and stimulate basic and clinical research in these disciplines and to promote new therapeutic strategies To encourage and stimulate basic and clinical research in these disciplines and to promote new therapeutic strategies To conduct scientific meetings relevant to these disciplines To conduct scientific meetings relevant to these disciplines International Society for Heart and Lung Transplantation: A Forum that Includes Basic Science, the Failing Heart and Advanced Lung Disease

5. ISHLT Goals To sponsor a scientific journal for the publication of manuscripts related to these disciplines To sponsor a scientific journal for the publication of manuscripts related to these disciplines To establish and maintain international registries for heart and lung transplantation, mechanical circulatory support, and related therapies To establish and maintain international registries for heart and lung transplantation, mechanical circulatory support, and related therapies To award research grants and establish endowments for the study of these disciplines To award research grants and establish endowments for the study of these disciplines International Society for Heart and Lung Transplantation: A Forum that Includes Basic Science, the Failing Heart and Advanced Lung Disease

6. Major Programs/Activities Annual Meeting and Scientific Sessions Annual Meeting and Scientific Sessions ISHLT Academy ISHLT Academy Journal of Heart and Lung Transplantation Journal of Heart and Lung Transplantation International Thoracic Transplant Registry International Thoracic Transplant Registry Quarterly Newsletter Quarterly Newsletter 10 Scientific Councils 10 Scientific Councils Transplant Research Fellowship Awards Transplant Research Fellowship Awards Career Development Awards Career Development Awards Professional Standards and Guidelines Professional Standards and Guidelines Monograph Series on Topics in End Stage Heart and Lung Disease Monograph Series on Topics in End Stage Heart and Lung Disease International Society for Heart and Lung Transplantation: A Forum that Includes Basic Science, the Failing Heart and Advanced Lung Disease

7. Current Projects Implementation of 20 key Strategic Planning goals regarding Education, Grants and Awards, Advocacy, Communications, Standards and Guidelines, Registries and Databases Implementation of 20 key Strategic Planning goals regarding Education, Grants and Awards, Advocacy, Communications, Standards and Guidelines, Registries and Databases Implementation of a new infrastructure for the Society designed to increase member involvement at the Council level, delegate implementation of more Society activities to newly established Committees, and free the Board to focus on strategic issues Implementation of a new infrastructure for the Society designed to increase member involvement at the Council level, delegate implementation of more Society activities to newly established Committees, and free the Board to focus on strategic issues International Society for Heart and Lung Transplantation: A Forum that Includes Basic Science, the Failing Heart and Advanced Lung Disease

8. Journal of Heart and Lung Transplantation 12 issues per year 12 issues per year ~625 manuscripts submitted annually (22% growth) ~625 manuscripts submitted annually (22% growth) 38% acceptance rate 38% acceptance rate Circulation of ~ 3100 Circulation of ~ 3100 High Impact Factor of 3.541 High Impact Factor of 3.541 Acceptance online publication = 4-6 weeks Acceptance online publication = 4-6 weeks Acceptance print publication = 3 months Acceptance print publication = 3 months International Society for Heart and Lung Transplantation: A Forum that Includes Basic Science, the Failing Heart and Advanced Lung Disease

9. Grants and Awards Program 60 Research Fellowship Grants 60 Research Fellowship Grants 6 Career Development Awards 6 Career Development Awards 30 Caves Best Paper Awards 30 Caves Best Paper Awards 2 MCS Fellowship Awards 2 MCS Fellowship Awards 3 Best MCS Paper Awards 3 Best MCS Paper Awards 15 Nursing Research Awards 15 Nursing Research Awards 5 Nursing Excellence Best Paper Awards 5 Nursing Excellence Best Paper Awards 6 Transplant Registry Early Career Awards 6 Transplant Registry Early Career Awards 4 Lifetime Achievement Awards 4 Lifetime Achievement Awards 2 Lifetime Service Awards 2 Lifetime Service Awards International Society for Heart and Lung Transplantation: A Forum that Includes Basic Science, the Failing Heart and Advanced Lung Disease

10. Scientific Councils Heart Failure & Transplant Medicine Heart Failure & Transplant Medicine Mechanical Circulatory Support Mechanical Circulatory Support Infectious Diseases Infectious Diseases Junior Faculty and Trainee Junior Faculty and Trainee Nursing, Health Science, and Allied Health Nursing, Health Science, and Allied Health Pathology Pathology Basic Science and Translational Research Basic Science and Translational Research Pediatric Transplantation Pediatric Transplantation Pulmonary Hypertension Pulmonary Hypertension Pulmonary Transplantation Pulmonary Transplantation

11. ISHLT Published Guidelines 2010: Guidelines for the Care of Cardiac Transplant Recipients 2010: Guidelines for the Care of Cardiac Transplant Recipients 2009: Generic Drug Immunosuppression in Thoracic Transplantation: An Educational Advisory 2009: Generic Drug Immunosuppression in Thoracic Transplantation: An Educational Advisory 2009: Advisory Statement on Pandemic Influenza 2009: Advisory Statement on Pandemic Influenza International Society for Heart and Lung Transplantation: A Forum that Includes Basic Science, the Failing Heart and Advanced Lung Disease

12. ISHLT Published Guidelines 2006: Guidelines for the Care of Cardiac Transplant Candidates 2006: Guidelines for the Care of Cardiac Transplant Candidates 2007: Revision of the 1996 Working Formulation for the Standardization of Nomenclature in the Diagnosis of Lung Rejection 2007: Revision of the 1996 Working Formulation for the Standardization of Nomenclature in the Diagnosis of Lung Rejection International Society for Heart and Lung Transplantation: A Forum that Includes Basic Science, the Failing Heart and Advanced Lung Disease

13. ISHLT Published Guidelines 2006: Present Status 2006: Present Status of Research on Psychosocial Outcomes in Cardiothoracic Transplantation: Review and Recommendations for the Field 2006: International Guidelines for the Selection of Lung Transplant Candidates: 2006 Update – A Consensus Report from the Pulmonary Council of ISHLT 2006: International Guidelines for the Selection of Lung Transplant Candidates: 2006 Update – A Consensus Report from the Pulmonary Council of ISHLT International Society for Heart and Lung Transplantation: A Forum that Includes Basic Science, the Failing Heart and Advanced Lung Disease

14. ISHLT Published Guidelines 2005: Report of the ISHLT Working Group on Primary Lung Graft Dysfunction: A Consensus Statement of the International Society for Heart and Lung Transplantation 2005: Report of the ISHLT Working Group on Primary Lung Graft Dysfunction: A Consensus Statement of the International Society for Heart and Lung Transplantation 2005: Revision of the 1990 Working Formulation for the Standardization of Nomenclature in the Diagnosis of Heart Rejection 2005: Revision of the 1990 Working Formulation for the Standardization of Nomenclature in the Diagnosis of Heart Rejection

15. ISHLT Published Guidelines 2004: ISHLT Practice Guidelines for Management of Heart Failure in Children 2004: ISHLT Practice Guidelines for Management of Heart Failure in Children 2003: A Review of Lung Transplant Donor Acceptability Criteria (a Consensus Report of the ISHLT Pulmonary Council) 2003: A Review of Lung Transplant Donor Acceptability Criteria (a Consensus Report of the ISHLT Pulmonary Council)

16. ISHLT Published Guidelines 2003: Destination Mechanical Circulatory Support: Proposal for Clinical Standards 2003: Destination Mechanical Circulatory Support: Proposal for Clinical Standards 2002: Maximizing Use of Organs Recovered from the Cadaver Donor: Cardiac Recommendations 2002: Maximizing Use of Organs Recovered from the Cadaver Donor: Cardiac Recommendations International Society for Heart and Lung Transplantation: A Forum that Includes Basic Science, the Failing Heart and Advanced Lung Disease

17. ISHLT Published Guidelines 2002: Bronchiolitis Obliterans Syndrome 2001: an Update of the Diagnostic Criteria 2002: Bronchiolitis Obliterans Syndrome 2001: an Update of the Diagnostic Criteria 2000: The Present Status of Xenotransplantation and its Potential Role in the Treatment of End-Stage Cardiac and Pulmonary Diseases 2000: The Present Status of Xenotransplantation and its Potential Role in the Treatment of End-Stage Cardiac and Pulmonary Diseases International Society for Heart and Lung Transplantation: A Forum that Includes Basic Science, the Failing Heart and Advanced Lung Disease

18. ISHLT Published Guidelines 1998: International Guidelines for the Selection of Lung Transplant Candidates. (With ATS, ASTP, ERS) 1998: International Guidelines for the Selection of Lung Transplant Candidates. (With ATS, ASTP, ERS) 1996: Revision of the 1990 Working Formulation for the Classification of Pulmonary Allograft Rejection 1996: Revision of the 1990 Working Formulation for the Classification of Pulmonary Allograft Rejection International Society for Heart and Lung Transplantation: A Forum that Includes Basic Science, the Failing Heart and Advanced Lung Disease

19. Future ISHLT Annual Meetings April 13-16, 2011 April 13-16, 2011 San Diego, CA, USA April 18-21, 2012 April 18-21, 2012 Prague, Czech Republic April, 24-27, 2013 April, 24-27, 2013 Montreal, Canada International Society for Heart and Lung Transplantation: A Forum that Includes Basic Science, the Failing Heart and Advanced Lung Disease

20. ISHLT Membership Professional Distribution International Society for Heart and Lung Transplantation: A Forum that Includes Basic Science, the Failing Heart and Advanced Lung Disease

21. ISHLT Membership Specialty Distribution SpecialtyPercentage Cardiovascular/Thoracic Surgeon 30% Cardiologist23% Pulmonologist11% Transplant Coordinator/Nurse 11% Researcher/Immunologist7% Pediatrics/Other /Unknown (anesthesiologist, pharmacist, perfusionist, etc) 18% International Society for Heart and Lung Transplantation: A Forum that Includes Basic Science, the Failing Heart and Advanced Lung Disease

22. ISHLT Membership Geographic Distribution International Society for Heart and Lung Transplantation: A Forum that Includes Basic Science, the Failing Heart and Advanced Lung Disease

23. ISHLT Membership Growth International Society for Heart and Lung Transplantation: A Forum that Includes Basic Science, the Failing Heart and Advanced Lung Disease

24. ISHLT Annual Meeting Attendance Growth International Society for Heart and Lung Transplantation: A Forum that Includes Basic Science, the Failing Heart and Advanced Lung Disease

25. ISHLT Annual Meeting Abstract Submission Growth International Society for Heart and Lung Transplantation: A Forum that Includes Basic Science, the Failing Heart and Advanced Lung Disease

26. ISHLT Sources of Revenue International Society for Heart and Lung Transplantation: A Forum that Includes Basic Science, the Failing Heart and Advanced Lung Disease

27. ISHLT Areas of Expense International Society for Heart and Lung Transplantation: A Forum that Includes Basic Science, the Failing Heart and Advanced Lung Disease