1. The History of the Microscope

2. What is a microscope?!
A biological tool which can be used to view objects that can’t be seen with the naked eye.
Objects such as…
Cells
Tissue
Microscopic Organisms
Mosquito
Blood Cells
Amoeba

3. 1000 AD First visionary aid was invented. Known as a Reading Stone
What do we call these today?

4. 1590
Janssen and Janssen first experimented with multiple lenses in a tube
(First Compound Microscope)
Compound Microscope Today

5. 1665 (The Discovery of the “Cell”)
Robert Hooke viewed cork under his microscope.
Called them Cells

6. 1674 (The Father of Microbiology)
Anton Van Leeuwenhoek
“Father of Microbiology”
Created Simple Microscope to view blood, yeast, and insects.
Invented knew methods in lens creation
Magnification up to 270 diameters

7. ’s
Improvements were made to increase magnification and viewing capabilities
Jackson reduces the spherical abberations on lenses
Reduced Image Blur
1903 – Zsigmondy develops ultramicroscope
Allowed scientists to view objects smaller than
wavelength of light (Noble Prize 1925)

8. 1931 (Electron Microscope)
Invented by Ernst Rusk
Uses electrons rather than light
Allows for the viewing of objects as small as the diameter of an atom.
Won Ernst Noble Prize in 1953
Rusk’s Electron Microscope (1930’s)
Electron Microscope Today

9. 1981 (Scanning Tunneling Microscope)
Invented by Binning and Rohrer
Allows for 3D magnification
Total Magnification 100,000,000X
Atomic Level
Birth of Nanoscience
Won Noble Prize 1986
Binning and Rohrer with their STM
Silicon Atoms
Surface of a piece of gold

10. Today
In Class
Compound Light Microscope
Stereo Microscope
HRTEM (High Resolution Transmission Electron Microscope)
Worlds “Best” Microscope
For Scientific Use
Total Mag = 47,000,000X
AFM (Atomic Force Microscope)
Worlds Most Powerful Microscope
Allows scientists to view individual atoms
Total Mag = >100,000,000X

11. High Resolution Transmission Electron Microscope
Stereo Microscope
Compound Microscope
High Resolution Transmission Electron Microscope
Atomic Force Microscope