1. From: Mechanisms of Murine Lacrimal Gland Repair after Experimentally Induced Inflammation
Invest. Ophthalmol. Vis. Sci ;49(10): doi: /iovs
Figure Legend:
The BMP7 pathway is activated during the repair phase. (A) Lacrimal gland homogenates prepared from control (C) and IL-1–treated animals were processed for Western blotting using an antibody against phosphorylated Smad1/5/8 or against β-actin (to control for gel loading). Data in the plot are mean ± SEM from three independent experiments. *Statistically significant difference from control. (B) Lacrimal glands removed from saline- and IL-1–treated animals were processed for immunofluorescence studies using the antibody against phosphorylated Smad1/5/8. (C) Lacrimal glands removed from IL-1–treated (3-day) animals were processed for double-immunofluorescence studies using anti-nestin (green) or anti-phosphorylated Smad1/5/8 (red). Nuclei were counterstained with DAPI (blue). Most of the nestin-positive cells were also positive for phosphorylated Smad1/5/8 (inset). Scale bar: (B, C) 50 μm.
Date of download: 9/18/2016
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